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Page 1
The antiproliferative cytostatic effects of a self-activating viridin prodrug.
Smith A, Blois J, Yuan H, Aikawa E, Ellson C, Figueiredo JL, Weissleder R, Kohler R, Yaffe MB, Cantley LC, Josephson L. Smith A, et al. Among authors: josephson l. Mol Cancer Ther. 2009 Jun;8(6):1666-75. doi: 10.1158/1535-7163.MCT-08-1012. Epub 2009 Jun 9. Mol Cancer Ther. 2009. PMID: 19509266 Free PMC article.
Slow self-activation enhances the potency of viridin prodrugs.
Blois J, Yuan H, Smith A, Pacold ME, Weissleder R, Cantley LC, Josephson L. Blois J, et al. Among authors: josephson l. J Med Chem. 2008 Aug 14;51(15):4699-707. doi: 10.1021/jm800374f. Epub 2008 Jul 17. J Med Chem. 2008. PMID: 18630894 Free PMC article.
Abrogation of antibody-induced arthritis in mice by a self-activating viridin prodrug and association with impaired neutrophil and endothelial cell function.
Stangenberg L, Ellson C, Cortez-Retamozo V, Ortiz-Lopez A, Yuan H, Blois J, Smith RA, Yaffe MB, Weissleder R, Benoist C, Mathis D, Josephson L, Mahmood U. Stangenberg L, et al. Among authors: josephson l. Arthritis Rheum. 2009 Aug;60(8):2314-24. doi: 10.1002/art.24704. Arthritis Rheum. 2009. PMID: 19644878 Free PMC article.
The slow cell death response when screening chemotherapeutic agents.
Blois J, Smith A, Josephson L. Blois J, et al. Among authors: josephson l. Cancer Chemother Pharmacol. 2011 Sep;68(3):795-803. doi: 10.1007/s00280-010-1549-9. Epub 2010 Dec 31. Cancer Chemother Pharmacol. 2011. PMID: 21193989 Free PMC article.
Wortmannin-C20 conjugates generate wortmannin.
Yuan H, Luo J, Weissleder R, Cantley L, Josephson L. Yuan H, et al. Among authors: josephson l. J Med Chem. 2006 Jan 26;49(2):740-7. doi: 10.1021/jm050699p. J Med Chem. 2006. PMID: 16420059
Fluorescent nanoparticle uptake for brain tumor visualization.
Tréhin R, Figueiredo JL, Pittet MJ, Weissleder R, Josephson L, Mahmood U. Tréhin R, et al. Among authors: josephson l. Neoplasia. 2006 Apr;8(4):302-11. doi: 10.1593/neo.05751. Neoplasia. 2006. PMID: 16756722 Free PMC article.
Fate of a bioactive fluorescent wortmannin derivative in cells.
Barnes KR, Blois J, Smith A, Yuan H, Reynolds F, Weissleder R, Cantley LC, Josephson L. Barnes KR, et al. Among authors: josephson l. Bioconjug Chem. 2008 Jan;19(1):130-7. doi: 10.1021/bc7002204. Epub 2007 Nov 8. Bioconjug Chem. 2008. PMID: 17988080
Real-time assessment of inflammation and treatment response in a mouse model of allergic airway inflammation.
Cortez-Retamozo V, Swirski FK, Waterman P, Yuan H, Figueiredo JL, Newton AP, Upadhyay R, Vinegoni C, Kohler R, Blois J, Smith A, Nahrendorf M, Josephson L, Weissleder R, Pittet MJ. Cortez-Retamozo V, et al. Among authors: josephson l. J Clin Invest. 2008 Dec;118(12):4058-66. doi: 10.1172/JCI36335. Epub 2008 Nov 6. J Clin Invest. 2008. PMID: 19033674 Free PMC article.
201 results