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A proprotein convertase subtilisin/kexin type 9 neutralizing antibody reduces serum cholesterol in mice and nonhuman primates.
Chan JC, Piper DE, Cao Q, Liu D, King C, Wang W, Tang J, Liu Q, Higbee J, Xia Z, Di Y, Shetterly S, Arimura Z, Salomonis H, Romanow WG, Thibault ST, Zhang R, Cao P, Yang XP, Yu T, Lu M, Retter MW, Kwon G, Henne K, Pan O, Tsai MM, Fuchslocher B, Yang E, Zhou L, Lee KJ, Daris M, Sheng J, Wang Y, Shen WD, Yeh WC, Emery M, Walker NP, Shan B, Schwarz M, Jackson SM. Chan JC, et al. Among authors: shen wd. Proc Natl Acad Sci U S A. 2009 Jun 16;106(24):9820-5. doi: 10.1073/pnas.0903849106. Epub 2009 May 14. Proc Natl Acad Sci U S A. 2009. PMID: 19443683 Free PMC article.
An inhibitory antibody against dipeptidyl peptidase IV improves glucose tolerance in vivo.
Tang J, Majeti J, Sudom A, Xiong Y, Lu M, Liu Q, Higbee J, Zhang Y, Wang Y, Wang W, Cao P, Xia Z, Johnstone S, Min X, Yang X, Shao H, Yu T, Sharkov N, Walker N, Tu H, Shen W, Wang Z. Tang J, et al. J Biol Chem. 2013 Jan 11;288(2):1307-16. doi: 10.1074/jbc.M112.396317. Epub 2012 Nov 26. J Biol Chem. 2013. PMID: 23184939 Free PMC article.
Monoclonal antibody expression in mammalian cells.
Zhang RY, Shen WD. Zhang RY, et al. Among authors: shen wd. Methods Mol Biol. 2012;907:341-58. doi: 10.1007/978-1-61779-974-7_20. Methods Mol Biol. 2012. PMID: 22907362
Generation of novel long-acting globular adiponectin molecules.
Ge H, Xiong Y, Lemon B, Lee KJ, Tang J, Wang P, Weiszmann J, Hawkins N, Laudemann J, Min X, Penny D, Wolfe T, Liu Q, Zhang R, Yeh WC, Shen W, Lindberg R, Wang Z, Sheng J, Li Y. Ge H, et al. J Mol Biol. 2010 May 28;399(1):113-9. doi: 10.1016/j.jmb.2010.03.062. Epub 2010 Apr 9. J Mol Biol. 2010. PMID: 20382165
Co-receptor requirements for fibroblast growth factor-19 signaling.
Wu X, Ge H, Gupte J, Weiszmann J, Shimamoto G, Stevens J, Hawkins N, Lemon B, Shen W, Xu J, Veniant MM, Li YS, Lindberg R, Chen JL, Tian H, Li Y. Wu X, et al. J Biol Chem. 2007 Oct 5;282(40):29069-72. doi: 10.1074/jbc.C700130200. Epub 2007 Aug 21. J Biol Chem. 2007. PMID: 17711860 Free article.
140 results