Li L - Search Results

1

Cytochrome P450 2D6 activity predicts discontinuation of tamoxifen therapy in breast cancer patients.

Rae JM, Sikora MJ, Henry NL, Li L, Kim S, Oesterreich S, Skaar TC, Nguyen AT, Desta Z, Storniolo AM, Flockhart DA, Hayes DF, Stearns V; COBRA investigators. Rae JM, et al. Among authors: li l. Pharmacogenomics J. 2009 Aug;9(4):258-64. doi: 10.1038/tpj.2009.14. Epub 2009 May 5. Pharmacogenomics J. 2009. PMID: 19421167 Free PMC article. Clinical Trial.

2

Pharmacokinetics and QT interval pharmacodynamics of oral haloperidol in poor and extensive metabolizers of CYP2D6.

Desai M, Tanus-Santos JE, Li L, Gorski JC, Arefayene M, Liu Y, Desta Z, Flockhart DA. Desai M, et al. Among authors: li l. Pharmacogenomics J. 2003;3(2):105-13. doi: 10.1038/sj.tpj.6500160. Pharmacogenomics J. 2003. PMID: 12746736 Clinical Trial.

3

Variability of heart rate correction methods for the QT interval.

Desai M, Li L, Desta Z, Malik M, Flockhart D. Desai M, et al. Among authors: li l. Br J Clin Pharmacol. 2003 Jun;55(6):511-7. doi: 10.1046/j.1365-2125.2003.01791.x. Br J Clin Pharmacol. 2003. PMID: 12814443 Free PMC article. Clinical Trial.

4

QT analysis: a complex answer to a 'simple' problem.

Li L, Desai M, Desta Z, Flockhart D. Li L, et al. Stat Med. 2004 Sep 15;23(17):2625-43. doi: 10.1002/sim.1863. Stat Med. 2004. PMID: 15316947

5

Association between the CYP3A5 genotype and blood pressure.

Ho H, Pinto A, Hall SD, Flockhart DA, Li L, Skaar TC, Cadman P, O'Connor DT, Wagner U, Fineberg NS, Weinberger MH. Ho H, et al. Among authors: li l. Hypertension. 2005 Feb;45(2):294-8. doi: 10.1161/01.HYP.0000151361.31736.96. Epub 2004 Dec 13. Hypertension. 2005. PMID: 15596575

6

CYP2D6 genotype, antidepressant use, and tamoxifen metabolism during adjuvant breast cancer treatment.

Jin Y, Desta Z, Stearns V, Ward B, Ho H, Lee KH, Skaar T, Storniolo AM, Li L, Araba A, Blanchard R, Nguyen A, Ullmer L, Hayden J, Lemler S, Weinshilboum RM, Rae JM, Hayes DF, Flockhart DA. Jin Y, et al. Among authors: li l. J Natl Cancer Inst. 2005 Jan 5;97(1):30-9. doi: 10.1093/jnci/dji005. J Natl Cancer Inst. 2005. PMID: 15632378

7

CYP2D6 genotype and tamoxifen response.

Rae JM, Goetz MP, Hayes DF, Ingle JN, Li L, Storniolo AM, Stearns V, Flockhart DA. Rae JM, et al. Among authors: li l. Breast Cancer Res. 2005 Jul 29;7(5):E6. doi: 10.1186/bcr1297. Breast Cancer Res. 2005. PMID: 16168100 Free PMC article. No abstract available.

8

Analysis of angiogenesis genes from paraffin-embedded breast tumor and lymph nodes.

Schneider BP, Skaar TC, Sledge GW, Badve S, Li L, Flockhart DA. Schneider BP, et al. Among authors: li l. Breast Cancer Res Treat. 2006 Apr;96(3):209-15. doi: 10.1007/s10549-005-9003-0. Epub 2006 Feb 28. Breast Cancer Res Treat. 2006. PMID: 16505966

9

Endoxifen, a secondary metabolite of tamoxifen, and 4-OH-tamoxifen induce similar changes in global gene expression patterns in MCF-7 breast cancer cells.

Lim YC, Li L, Desta Z, Zhao Q, Rae JM, Flockhart DA, Skaar TC. Lim YC, et al. Among authors: li l. J Pharmacol Exp Ther. 2006 Aug;318(2):503-12. doi: 10.1124/jpet.105.100511. Epub 2006 May 11. J Pharmacol Exp Ther. 2006. PMID: 16690721

10

Quantitative effect of CYP2D6 genotype and inhibitors on tamoxifen metabolism: implication for optimization of breast cancer treatment.

Borges S, Desta Z, Li L, Skaar TC, Ward BA, Nguyen A, Jin Y, Storniolo AM, Nikoloff DM, Wu L, Hillman G, Hayes DF, Stearns V, Flockhart DA. Borges S, et al. Among authors: li l. Clin Pharmacol Ther. 2006 Jul;80(1):61-74. doi: 10.1016/j.clpt.2006.03.013. Clin Pharmacol Ther. 2006. PMID: 16815318 Free article.

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