Hamstra HJ - Search Results

1

Identification of a novel lipopolysaccharide core biosynthesis gene cluster in Bordetella pertussis, and influence of core structure and lipid A glucosamine substitution on endotoxic activity.

Geurtsen J, Dzieciatkowska M, Steeghs L, Hamstra HJ, Boleij J, Broen K, Akkerman G, El Hassan H, Li J, Richards JC, Tommassen J, van der Ley P. Geurtsen J, et al. Among authors: hamstra hj. Infect Immun. 2009 Jul;77(7):2602-11. doi: 10.1128/IAI.00033-09. Epub 2009 Apr 13. Infect Immun. 2009. PMID: 19364841 Free PMC article.

2

Expression of the lipopolysaccharide-modifying enzymes PagP and PagL modulates the endotoxic activity of Bordetella pertussis.

Geurtsen J, Steeghs L, Hamstra HJ, Ten Hove J, de Haan A, Kuipers B, Tommassen J, van der Ley P. Geurtsen J, et al. Among authors: hamstra hj. Infect Immun. 2006 Oct;74(10):5574-85. doi: 10.1128/IAI.00834-06. Infect Immun. 2006. PMID: 16988232 Free PMC article.

3

A novel secondary acyl chain in the lipopolysaccharide of Bordetella pertussis required for efficient infection of human macrophages.

Geurtsen J, Angevaare E, Janssen M, Hamstra HJ, ten Hove J, de Haan A, Kuipers B, Tommassen J, van der Ley P. Geurtsen J, et al. Among authors: hamstra hj. J Biol Chem. 2007 Dec 28;282(52):37875-84. doi: 10.1074/jbc.M706391200. Epub 2007 Oct 29. J Biol Chem. 2007. PMID: 17967899 Free article.

4

Modification of lipid A biosynthesis in Neisseria meningitidis lpxL mutants: influence on lipopolysaccharide structure, toxicity, and adjuvant activity.

van der Ley P, Steeghs L, Hamstra HJ, ten Hove J, Zomer B, van Alphen L. van der Ley P, et al. Among authors: hamstra hj. Infect Immun. 2001 Oct;69(10):5981-90. doi: 10.1128/IAI.69.10.5981-5990.2001. Infect Immun. 2001. PMID: 11553534 Free PMC article.

5

Coincorporation of LpxL1 and PagL mutant lipopolysaccharides into liposomes with Neisseria meningitidis opacity protein: influence on endotoxic and adjuvant activity.

Arenas J, van Dijken H, Kuipers B, Hamstra HJ, Tommassen J, van der Ley P. Arenas J, et al. Among authors: hamstra hj. Clin Vaccine Immunol. 2010 Apr;17(4):487-95. doi: 10.1128/CVI.00423-09. Epub 2010 Jan 27. Clin Vaccine Immunol. 2010. PMID: 20107001 Free PMC article.

6

The structure of Neisseria meningitidis lipid A determines outcome in experimental meningococcal disease.

Fransen F, Hamstra HJ, Boog CJ, van Putten JP, van den Dobbelsteen GP, van der Ley P. Fransen F, et al. Among authors: hamstra hj. Infect Immun. 2010 Jul;78(7):3177-86. doi: 10.1128/IAI.01311-09. Epub 2010 May 3. Infect Immun. 2010. PMID: 20439476 Free PMC article.

7

Bordetella pertussis naturally occurring isolates with altered lipooligosaccharide structure fail to fully mature human dendritic cells.

Brummelman J, Veerman RE, Hamstra HJ, Deuss AJ, Schuijt TJ, Sloots A, Kuipers B, van Els CA, van der Ley P, Mooi FR, Han WG, Pinelli E. Brummelman J, et al. Among authors: hamstra hj. Infect Immun. 2015 Jan;83(1):227-38. doi: 10.1128/IAI.02197-14. Epub 2014 Oct 27. Infect Immun. 2015. PMID: 25348634 Free PMC article.

8

Meningococcal Outer Membrane Vesicle Composition-Dependent Activation of the Innate Immune Response.

Zariri A, Beskers J, van de Waterbeemd B, Hamstra HJ, Bindels TH, van Riet E, van Putten JP, van der Ley P. Zariri A, et al. Among authors: hamstra hj. Infect Immun. 2016 Sep 19;84(10):3024-33. doi: 10.1128/IAI.00635-16. Print 2016 Oct. Infect Immun. 2016. PMID: 27481244 Free PMC article.

9

Immunogenicity of outer membrane proteins in a lipopolysaccharide-deficient mutant of Neisseria meningitidis: influence of adjuvants on the immune response.

Steeghs L, Kuipers B, Hamstra HJ, Kersten G, van Alphen L, van der Ley P. Steeghs L, et al. Among authors: hamstra hj. Infect Immun. 1999 Oct;67(10):4988-93. doi: 10.1128/IAI.67.10.4988-4993.1999. Infect Immun. 1999. PMID: 10496868 Free PMC article.

10

Altered linkage of hydroxyacyl chains in lipid A of Campylobacter jejuni reduces TLR4 activation and antimicrobial resistance.

van Mourik A, Steeghs L, van Laar J, Meiring HD, Hamstra HJ, van Putten JP, Wösten MM. van Mourik A, et al. Among authors: hamstra hj. J Biol Chem. 2010 May 21;285(21):15828-36. doi: 10.1074/jbc.M110.102061. Epub 2010 Mar 29. J Biol Chem. 2010. PMID: 20351099 Free PMC article.

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