Sinz MW - Search Results

1

Frequency of CYP1A2 polymorphism in beagle dogs.

Whiterock VJ, Delmonte TA, Hui LE, Orcutt TL, Sinz MW. Whiterock VJ, et al. Among authors: sinz mw. Drug Metab Lett. 2007 Apr;1(2):163-5. doi: 10.2174/187231207780363688. Drug Metab Lett. 2007. PMID: 19356037

2

Phenacetin pharmacokinetics in CYP1A2-deficient beagle dogs.

Whiterock VJ, Morgan DG, Lentz KA, Orcutt TL, Sinz MW. Whiterock VJ, et al. Among authors: sinz mw. Drug Metab Dispos. 2012 Feb;40(2):228-31. doi: 10.1124/dmd.111.041848. Epub 2011 Nov 10. Drug Metab Dispos. 2012. PMID: 22074769

3

Evaluation of cynomolgus monkey pregnane X receptor, primary hepatocyte, and in vivo pharmacokinetic changes in predicting human CYP3A4 induction.

Kim S, Dinchuk JE, Anthony MN, Orcutt T, Zoeckler ME, Sauer MB, Mosure KW, Vuppugalla R, Grace JE Jr, Simmermacher J, Dulac HA, Pizzano J, Sinz M. Kim S, et al. Drug Metab Dispos. 2010 Jan;38(1):16-24. doi: 10.1124/dmd.109.029637. Drug Metab Dispos. 2010. PMID: 19833845

4

Quantitative relationship between rifampicin exposure and induction of Cyp3a11 in SXR humanized mice: extrapolation to human CYP3A4 induction potential.

Kim S, Pray D, Zheng M, Morgan DG, Pizzano JG, Zoeckler ME, Chimalakonda A, Sinz MW. Kim S, et al. Among authors: sinz mw. Drug Metab Lett. 2008 Aug;2(3):169-75. doi: 10.2174/187231208785425809. Drug Metab Lett. 2008. PMID: 19356089

5

The utility of stable cell lines to assess species differences in PXR transactivation.

Sinz MW, Pray D, Raucy J. Sinz MW, et al. Drug Metab Lett. 2007 Apr;1(2):147-52. doi: 10.2174/187231207780363561. Drug Metab Lett. 2007. PMID: 19356035

6

Cytochrome P450 reaction-phenotyping: an industrial perspective.

Zhang H, Davis CD, Sinz MW, Rodrigues AD. Zhang H, et al. Among authors: sinz mw. Expert Opin Drug Metab Toxicol. 2007 Oct;3(5):667-87. doi: 10.1517/17425255.3.5.667. Expert Opin Drug Metab Toxicol. 2007. PMID: 17916054 Review.

7

Evaluation of Farnesoid X Receptor Target Gene Induction in Human Hepatocytes: Amino Acid Conjugation.

Simmermacher J, Sinz M. Simmermacher J, et al. Drug Metab Lett. 2017;11(2):138-143. doi: 10.2174/1872312812666171227213946. Drug Metab Lett. 2017. PMID: 29283075

8

Evaluation of pregnane X receptor (PXR)-mediated CYP3A4 drug-drug interactions in drug development.

Sinz MW. Sinz MW. Drug Metab Rev. 2013 Feb;45(1):3-14. doi: 10.3109/03602532.2012.743560. Drug Metab Rev. 2013. PMID: 23330538 Review.

9

Evaluation of 170 xenobiotics as transactivators of human pregnane X receptor (hPXR) and correlation to known CYP3A4 drug interactions.

Sinz M, Kim S, Zhu Z, Chen T, Anthony M, Dickinson K, Rodrigues AD. Sinz M, et al. Curr Drug Metab. 2006 May;7(4):375-88. doi: 10.2174/138920006776873535. Curr Drug Metab. 2006. PMID: 16724927

10

A Novel Liquid Chromatography Tandem Mass Spectrometry Method for the Estimation of Bilirubin Glucuronides and its Application to In Vitro Enzyme Assays.

Putluru SP, Matta MK, Ahire D, Subramanian M, Sinz M, Mandlekar S. Putluru SP, et al. Drug Metab Lett. 2017;10(4):264-269. doi: 10.2174/1872312810666161124143522. Drug Metab Lett. 2017. PMID: 27908259

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