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PTEN loss contributes to erlotinib resistance in EGFR-mutant lung cancer by activation of Akt and EGFR.
Sos ML, Koker M, Weir BA, Heynck S, Rabinovsky R, Zander T, Seeger JM, Weiss J, Fischer F, Frommolt P, Michel K, Peifer M, Mermel C, Girard L, Peyton M, Gazdar AF, Minna JD, Garraway LA, Kashkar H, Pao W, Meyerson M, Thomas RK. Sos ML, et al. Among authors: kashkar h. Cancer Res. 2009 Apr 15;69(8):3256-61. doi: 10.1158/0008-5472.CAN-08-4055. Epub 2009 Apr 7. Cancer Res. 2009. PMID: 19351834 Free PMC article.
Identifying genotype-dependent efficacy of single and combined PI3K- and MAPK-pathway inhibition in cancer.
Sos ML, Fischer S, Ullrich R, Peifer M, Heuckmann JM, Koker M, Heynck S, Stückrath I, Weiss J, Fischer F, Michel K, Goel A, Regales L, Politi KA, Perera S, Getlik M, Heukamp LC, Ansén S, Zander T, Beroukhim R, Kashkar H, Shokat KM, Sellers WR, Rauh D, Orr C, Hoeflich KP, Friedman L, Wong KK, Pao W, Thomas RK. Sos ML, et al. Among authors: kashkar h. Proc Natl Acad Sci U S A. 2009 Oct 27;106(43):18351-6. doi: 10.1073/pnas.0907325106. Epub 2009 Oct 5. Proc Natl Acad Sci U S A. 2009. PMID: 19805051 Free PMC article.
Elevated XIAP expression alone does not confer chemoresistance.
Seeger JM, Brinkmann K, Yazdanpanah B, Haubert D, Pongratz C, Coutelle O, Krönke M, Kashkar H. Seeger JM, et al. Among authors: kashkar h. Br J Cancer. 2010 Jun 8;102(12):1717-23. doi: 10.1038/sj.bjc.6605704. Epub 2010 May 18. Br J Cancer. 2010. PMID: 20485285 Free PMC article.
Dimethylfumarate induces apoptosis in human mast cells.
Förster A, Preussner LM, Seeger JM, Rabenhorst A, Kashkar H, Mrowietz U, Hartmann K. Förster A, et al. Among authors: kashkar h. Exp Dermatol. 2013 Nov;22(11):719-24. doi: 10.1111/exd.12247. Exp Dermatol. 2013. PMID: 24112621
Tumour-infiltrating neutrophils counteract anti-VEGF therapy in metastatic colorectal cancer.
Schiffmann LM, Fritsch M, Gebauer F, Günther SD, Stair NR, Seeger JM, Thangarajah F, Dieplinger G, Bludau M, Alakus H, Göbel H, Quaas A, Zander T, Hilberg F, Bruns CJ, Kashkar H, Coutelle O. Schiffmann LM, et al. Among authors: kashkar h. Br J Cancer. 2019 Jan;120(1):69-78. doi: 10.1038/s41416-018-0198-3. Epub 2018 Oct 31. Br J Cancer. 2019. PMID: 30377339 Free PMC article.
Streptococcus pneumoniae serotype 1 capsular polysaccharide induces CD8CD28 regulatory T lymphocytes by TCR crosslinking.
Mertens J, Fabri M, Zingarelli A, Kubacki T, Meemboor S, Groneck L, Seeger J, Bessler M, Hafke H, Odenthal M, Bieler JG, Kalka C, Schneck JP, Kashkar H, Kalka-Moll WM. Mertens J, et al. Among authors: kashkar h. PLoS Pathog. 2009 Sep;5(9):e1000596. doi: 10.1371/journal.ppat.1000596. Epub 2009 Sep 25. PLoS Pathog. 2009. PMID: 19779562 Free PMC article.
Interleukin-6 is essential for zwitterionic polysaccharide-mediated abscess formation.
Meemboor S, Mertens J, Flenner E, Groneck L, Zingarelli A, Gamstätter T, Bessler M, Seeger JM, Kashkar H, Odenthal M, Kalka-Moll WM. Meemboor S, et al. Among authors: kashkar h. Innate Immun. 2010 Oct;16(5):310-21. doi: 10.1177/1753425909346974. Epub 2009 Nov 6. Innate Immun. 2010. PMID: 19897529 Free article.
89 results