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Donor treatment with a PHD-inhibitor activating HIFs prevents graft injury and prolongs survival in an allogenic kidney transplant model.
Bernhardt WM, Gottmann U, Doyon F, Buchholz B, Campean V, Schödel J, Reisenbuechler A, Klaus S, Arend M, Flippin L, Willam C, Wiesener MS, Yard B, Warnecke C, Eckardt KU. Bernhardt WM, et al. Among authors: warnecke c. Proc Natl Acad Sci U S A. 2009 Dec 15;106(50):21276-81. doi: 10.1073/pnas.0903978106. Epub 2009 Nov 23. Proc Natl Acad Sci U S A. 2009. PMID: 19934037 Free PMC article.
Role of hypoxia in the pathogenesis of renal disease.
Eckardt KU, Bernhardt WM, Weidemann A, Warnecke C, Rosenberger C, Wiesener MS, Willam C. Eckardt KU, et al. Among authors: warnecke c. Kidney Int Suppl. 2005 Dec;(99):S46-51. doi: 10.1111/j.1523-1755.2005.09909.x. Kidney Int Suppl. 2005. PMID: 16336576 Free article. Review.
The tumor gene survivin is highly expressed in adult renal tubular cells: implications for a pathophysiological role in the kidney.
Lechler P, Wu X, Bernhardt W, Campean V, Gastiger S, Hackenbeck T, Klanke B, Weidemann A, Warnecke C, Amann K, Engehausen D, Willam C, Eckardt KU, Rödel F, Wiesener MS. Lechler P, et al. Among authors: warnecke c. Am J Pathol. 2007 Nov;171(5):1483-98. doi: 10.2353/ajpath.2007.070132. Am J Pathol. 2007. PMID: 17982126 Free PMC article.
Organ protection by hypoxia and hypoxia-inducible factors.
Bernhardt WM, Warnecke C, Willam C, Tanaka T, Wiesener MS, Eckardt KU. Bernhardt WM, et al. Among authors: warnecke c. Methods Enzymol. 2007;435:221-45. doi: 10.1016/S0076-6879(07)35012-X. Methods Enzymol. 2007. PMID: 17998057 Review.
HIF activation protects from acute kidney injury.
Weidemann A, Bernhardt WM, Klanke B, Daniel C, Buchholz B, Câmpean V, Amann K, Warnecke C, Wiesener MS, Eckardt KU, Willam C. Weidemann A, et al. Among authors: warnecke c. J Am Soc Nephrol. 2008 Mar;19(3):486-94. doi: 10.1681/ASN.2007040419. Epub 2008 Feb 6. J Am Soc Nephrol. 2008. PMID: 18256363 Free PMC article.
74 results