Houghton AN - Search Results

1

Self-antigen-specific CD8+ T cell precursor frequency determines the quality of the antitumor immune response.

Rizzuto GA, Merghoub T, Hirschhorn-Cymerman D, Liu C, Lesokhin AM, Sahawneh D, Zhong H, Panageas KS, Perales MA, Altan-Bonnet G, Wolchok JD, Houghton AN. Rizzuto GA, et al. Among authors: houghton an. J Exp Med. 2009 Apr 13;206(4):849-66. doi: 10.1084/jem.20081382. Epub 2009 Mar 30. J Exp Med. 2009. PMID: 19332877 Free PMC article.

2

Immunity to cancer through immune recognition of altered self: studies with melanoma.

Guevara-Patiño JA, Turk MJ, Wolchok JD, Houghton AN. Guevara-Patiño JA, et al. Among authors: houghton an. Adv Cancer Res. 2003;90:157-77. doi: 10.1016/s0065-230x(03)90005-4. Adv Cancer Res. 2003. PMID: 14710950 Review.

3

Concomitant tumor immunity to a poorly immunogenic melanoma is prevented by regulatory T cells.

Turk MJ, Guevara-Patiño JA, Rizzuto GA, Engelhorn ME, Sakaguchi S, Houghton AN. Turk MJ, et al. Among authors: houghton an. J Exp Med. 2004 Sep 20;200(6):771-82. doi: 10.1084/jem.20041130. J Exp Med. 2004. PMID: 15381730 Free PMC article.

4

Optimization of a self antigen for presentation of multiple epitopes in cancer immunity.

Guevara-Patiño JA, Engelhorn ME, Turk MJ, Liu C, Duan F, Rizzuto G, Cohen AD, Merghoub T, Wolchok JD, Houghton AN. Guevara-Patiño JA, et al. Among authors: houghton an. J Clin Invest. 2006 May;116(5):1382-90. doi: 10.1172/JCI25591. Epub 2006 Apr 13. J Clin Invest. 2006. PMID: 16614758 Free PMC article.

5

Agonist anti-GITR antibody enhances vaccine-induced CD8(+) T-cell responses and tumor immunity.

Cohen AD, Diab A, Perales MA, Wolchok JD, Rizzuto G, Merghoub T, Huggins D, Liu C, Turk MJ, Restifo NP, Sakaguchi S, Houghton AN. Cohen AD, et al. Among authors: houghton an. Cancer Res. 2006 May 1;66(9):4904-12. doi: 10.1158/0008-5472.CAN-05-2813. Cancer Res. 2006. PMID: 16651447 Free PMC article.

6

Immune rejection of mouse tumors expressing mutated self.

Duan F, Lin Y, Liu C, Engelhorn ME, Cohen AD, Curran M, Sakaguchi S, Merghoub T, Terzulli S, Wolchok JD, Houghton AN. Duan F, et al. Among authors: houghton an. Cancer Res. 2009 Apr 15;69(8):3545-53. doi: 10.1158/0008-5472.CAN-08-2779. Epub 2009 Apr 7. Cancer Res. 2009. PMID: 19351857 Free PMC article.

7

OX40 engagement and chemotherapy combination provides potent antitumor immunity with concomitant regulatory T cell apoptosis.

Hirschhorn-Cymerman D, Rizzuto GA, Merghoub T, Cohen AD, Avogadri F, Lesokhin AM, Weinberg AD, Wolchok JD, Houghton AN. Hirschhorn-Cymerman D, et al. Among authors: houghton an. J Exp Med. 2009 May 11;206(5):1103-16. doi: 10.1084/jem.20082205. Epub 2009 May 4. J Exp Med. 2009. PMID: 19414558 Free PMC article.

8

Detection of intra-tumor self antigen recognition during melanoma tumor progression in mice using advanced multimode confocal/two photon microscope.

Schaer DA, Li Y, Merghoub T, Rizzuto GA, Shemesh A, Cohen AD, Li Y, Avogadri F, Toledo-Crow R, Houghton AN, Wolchok JD. Schaer DA, et al. Among authors: houghton an. PLoS One. 2011;6(6):e21214. doi: 10.1371/journal.pone.0021214. Epub 2011 Jun 22. PLoS One. 2011. PMID: 21731676 Free PMC article.

9

Monocytic CCR2(+) myeloid-derived suppressor cells promote immune escape by limiting activated CD8 T-cell infiltration into the tumor microenvironment.

Lesokhin AM, Hohl TM, Kitano S, Cortez C, Hirschhorn-Cymerman D, Avogadri F, Rizzuto GA, Lazarus JJ, Pamer EG, Houghton AN, Merghoub T, Wolchok JD. Lesokhin AM, et al. Among authors: houghton an. Cancer Res. 2012 Feb 15;72(4):876-86. doi: 10.1158/0008-5472.CAN-11-1792. Epub 2011 Dec 15. Cancer Res. 2012. PMID: 22174368 Free PMC article.

10

Induction of tumoricidal function in CD4+ T cells is associated with concomitant memory and terminally differentiated phenotype.

Hirschhorn-Cymerman D, Budhu S, Kitano S, Liu C, Zhao F, Zhong H, Lesokhin AM, Avogadri-Connors F, Yuan J, Li Y, Houghton AN, Merghoub T, Wolchok JD. Hirschhorn-Cymerman D, et al. Among authors: houghton an. J Exp Med. 2012 Oct 22;209(11):2113-26. doi: 10.1084/jem.20120532. Epub 2012 Sep 24. J Exp Med. 2012. PMID: 23008334 Free PMC article.

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