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Cellular content of UDP-N-acetylhexosamines controls hyaluronan synthase 2 expression and correlates with O-linked N-acetylglucosamine modification of transcription factors YY1 and SP1.
Jokela TA, Makkonen KM, Oikari S, Kärnä R, Koli E, Hart GW, Tammi RH, Carlberg C, Tammi MI. Jokela TA, et al. Among authors: karna r. J Biol Chem. 2011 Sep 23;286(38):33632-40. doi: 10.1074/jbc.M111.265637. Epub 2011 Jul 27. J Biol Chem. 2011. PMID: 21795679 Free PMC article.
Hyaluronan production enhances shedding of plasma membrane-derived microvesicles.
Rilla K, Pasonen-Seppänen S, Deen AJ, Koistinen VVT, Wojciechowski S, Oikari S, Kärnä R, Bart G, Törrönen K, Tammi RH, Tammi MI. Rilla K, et al. Among authors: karna r. Exp Cell Res. 2013 Aug 1;319(13):2006-2018. doi: 10.1016/j.yexcr.2013.05.021. Epub 2013 Jun 1. Exp Cell Res. 2013. PMID: 23732660
Extracellular UDP-glucose activates P2Y14 Receptor and Induces Signal Transducer and Activator of Transcription 3 (STAT3) Tyr705 phosphorylation and binding to hyaluronan synthase 2 (HAS2) promoter, stimulating hyaluronan synthesis of keratinocytes.
Jokela TA, Kärnä R, Makkonen KM, Laitinen JT, Tammi RH, Tammi MI. Jokela TA, et al. Among authors: karna r. J Biol Chem. 2014 Jun 27;289(26):18569-81. doi: 10.1074/jbc.M114.551804. Epub 2014 May 20. J Biol Chem. 2014. PMID: 24847057 Free PMC article.
79 results