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Mutations in the FUS/TLS gene on chromosome 16 cause familial amyotrophic lateral sclerosis.
Kwiatkowski TJ Jr, Bosco DA, Leclerc AL, Tamrazian E, Vanderburg CR, Russ C, Davis A, Gilchrist J, Kasarskis EJ, Munsat T, Valdmanis P, Rouleau GA, Hosler BA, Cortelli P, de Jong PJ, Yoshinaga Y, Haines JL, Pericak-Vance MA, Yan J, Ticozzi N, Siddique T, McKenna-Yasek D, Sapp PC, Horvitz HR, Landers JE, Brown RH Jr. Kwiatkowski TJ Jr, et al. Among authors: vanderburg cr. Science. 2009 Feb 27;323(5918):1205-8. doi: 10.1126/science.1166066. Science. 2009. PMID: 19251627
Tau protein liquid-liquid phase separation can initiate tau aggregation.
Wegmann S, Eftekharzadeh B, Tepper K, Zoltowska KM, Bennett RE, Dujardin S, Laskowski PR, MacKenzie D, Kamath T, Commins C, Vanderburg C, Roe AD, Fan Z, Molliex AM, Hernandez-Vega A, Muller D, Hyman AA, Mandelkow E, Taylor JP, Hyman BT. Wegmann S, et al. EMBO J. 2018 Apr 3;37(7):e98049. doi: 10.15252/embj.201798049. Epub 2018 Feb 22. EMBO J. 2018. PMID: 29472250 Free PMC article.
No alteration in tau exon 10 alternative splicing in tangle-bearing neurons of the Alzheimer's disease brain.
Ingelsson M, Ramasamy K, Cantuti-Castelvetri I, Skoglund L, Matsui T, Orne J, Kowa H, Raju S, Vanderburg CR, Augustinack JC, de Silva R, Lees AJ, Lannfelt L, Growdon JH, Frosch MP, Standaert DG, Irizarry MC, Hyman BT. Ingelsson M, et al. Among authors: vanderburg cr. Acta Neuropathol. 2006 Oct;112(4):439-49. doi: 10.1007/s00401-006-0095-3. Epub 2006 Jun 27. Acta Neuropathol. 2006. PMID: 16802167
Exosomal cell-to-cell transmission of alpha synuclein oligomers.
Danzer KM, Kranich LR, Ruf WP, Cagsal-Getkin O, Winslow AR, Zhu L, Vanderburg CR, McLean PJ. Danzer KM, et al. Among authors: vanderburg cr. Mol Neurodegener. 2012 Aug 24;7:42. doi: 10.1186/1750-1326-7-42. Mol Neurodegener. 2012. PMID: 22920859 Free PMC article.
Tau Protein Disrupts Nucleocytoplasmic Transport in Alzheimer's Disease.
Eftekharzadeh B, Daigle JG, Kapinos LE, Coyne A, Schiantarelli J, Carlomagno Y, Cook C, Miller SJ, Dujardin S, Amaral AS, Grima JC, Bennett RE, Tepper K, DeTure M, Vanderburg CR, Corjuc BT, DeVos SL, Gonzalez JA, Chew J, Vidensky S, Gage FH, Mertens J, Troncoso J, Mandelkow E, Salvatella X, Lim RYH, Petrucelli L, Wegmann S, Rothstein JD, Hyman BT. Eftekharzadeh B, et al. Among authors: vanderburg cr. Neuron. 2018 Sep 5;99(5):925-940.e7. doi: 10.1016/j.neuron.2018.07.039. Neuron. 2018. PMID: 30189209 Free PMC article.
Tau Protein Disrupts Nucleocytoplasmic Transport in Alzheimer's Disease.
Eftekharzadeh B, Daigle JG, Kapinos LE, Coyne A, Schiantarelli J, Carlomagno Y, Cook C, Miller SJ, Dujardin S, Amaral AS, Grima JC, Bennett RE, Tepper K, DeTure M, Vanderburg CR, Corjuc BT, DeVos SL, Gonzalez JA, Chew J, Vidensky S, Gage FH, Mertens J, Troncoso J, Mandelkow E, Salvatella X, Lim RYH, Petrucelli L, Wegmann S, Rothstein JD, Hyman BT. Eftekharzadeh B, et al. Among authors: vanderburg cr. Neuron. 2019 Jan 16;101(2):349. doi: 10.1016/j.neuron.2018.12.031. Neuron. 2019. PMID: 30653936 Free PMC article. No abstract available.
69 results