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Select pyrimidinones inhibit the propagation of the malarial parasite, Plasmodium falciparum.
Chiang AN, Valderramos JC, Balachandran R, Chovatiya RJ, Mead BP, Schneider C, Bell SL, Klein MG, Huryn DM, Chen XS, Day BW, Fidock DA, Wipf P, Brodsky JL. Chiang AN, et al. Among authors: wipf p. Bioorg Med Chem. 2009 Feb 15;17(4):1527-33. doi: 10.1016/j.bmc.2009.01.024. Epub 2009 Jan 20. Bioorg Med Chem. 2009. PMID: 19195901 Free PMC article.
Identification of new Cdc25 dual specificity phosphatase inhibitors in a targeted small molecule array.
Ducruet AP, Rice RL, Tamura K, Yokokawa F, Yokokawa S, Wipf P, Lazo JS. Ducruet AP, et al. Among authors: wipf p. Bioorg Med Chem. 2000 Jun;8(6):1451-66. doi: 10.1016/s0968-0896(00)00069-9. Bioorg Med Chem. 2000. PMID: 10896122
.; Yokokawa, S.; Messner, D. J.; Boynton, A. L.; Wipf, P.; Lazo, J. S. Biochemistry 1997, 36, 15965). Several analogues were identified as effective inhibitors of the protein tyrosine phosphatase (PTPase) PTP1B and the DSPases VHR and Cdc25B2. ...
.; Yokokawa, S.; Messner, D. J.; Boynton, A. L.; Wipf, P.; Lazo, J. S. Biochemistry 1997, 36, 15965). Several analogues were i …
Chemistry and biology of curacin A.
Wipf P, Reeves JT, Day BW. Wipf P, et al. Curr Pharm Des. 2004;10(12):1417-37. doi: 10.2174/1381612043384853. Curr Pharm Des. 2004. PMID: 15134491 Review.
459 results