Do ZN - Search Results

1

Non-urea functionality as the primary pharmacophore in soluble epoxide hydrolase inhibitors.

Anandan SK, Do ZN, Webb HK, Patel DV, Gless RD. Anandan SK, et al. Among authors: do zn. Bioorg Med Chem Lett. 2009 Feb 15;19(4):1066-70. doi: 10.1016/j.bmcl.2009.01.013. Epub 2009 Jan 10. Bioorg Med Chem Lett. 2009. PMID: 19168352

2

Unsymmetrical non-adamantyl N,N'-diaryl urea and amide inhibitors of soluble expoxide hydrolase.

Anandan SK, Webb HK, Do ZN, Gless RD. Anandan SK, et al. Among authors: do zn. Bioorg Med Chem Lett. 2009 Aug 1;19(15):4259-63. doi: 10.1016/j.bmcl.2009.05.102. Epub 2009 May 30. Bioorg Med Chem Lett. 2009. PMID: 19520575

3

1-(1-acetyl-piperidin-4-yl)-3-adamantan-1-yl-urea (AR9281) as a potent, selective, and orally available soluble epoxide hydrolase inhibitor with efficacy in rodent models of hypertension and dysglycemia.

Anandan SK, Webb HK, Chen D, Wang YX, Aavula BR, Cases S, Cheng Y, Do ZN, Mehra U, Tran V, Vincelette J, Waszczuk J, White K, Wong KR, Zhang LN, Jones PD, Hammock BD, Patel DV, Whitcomb R, MacIntyre DE, Sabry J, Gless R. Anandan SK, et al. Among authors: do zn. Bioorg Med Chem Lett. 2011 Feb 1;21(3):983-8. doi: 10.1016/j.bmcl.2010.12.042. Epub 2010 Dec 13. Bioorg Med Chem Lett. 2011. PMID: 21211973 Free PMC article.

4

Pharmacokinetics and pharmacodynamics of AR9281, an inhibitor of soluble epoxide hydrolase, in single- and multiple-dose studies in healthy human subjects.

Chen D, Whitcomb R, MacIntyre E, Tran V, Do ZN, Sabry J, Patel DV, Anandan SK, Gless R, Webb HK. Chen D, et al. Among authors: do zn. J Clin Pharmacol. 2012 Mar;52(3):319-28. doi: 10.1177/0091270010397049. Epub 2011 Mar 21. J Clin Pharmacol. 2012. PMID: 21422238 Clinical Trial.

5

Solid-phase combinatorial approach for the optimization of soluble epoxide hydrolase inhibitors.

Hwang SH, Morisseau C, Do Z, Hammock BD. Hwang SH, et al. Bioorg Med Chem Lett. 2006 Nov 15;16(22):5773-7. doi: 10.1016/j.bmcl.2006.08.078. Epub 2006 Sep 1. Bioorg Med Chem Lett. 2006. PMID: 16949285 Free PMC article.

6

Synthesis and SAR of conformationally restricted inhibitors of soluble epoxide hydrolase.

Jones PD, Tsai HJ, Do ZN, Morisseau C, Hammock BD. Jones PD, et al. Among authors: do zn. Bioorg Med Chem Lett. 2006 Oct 1;16(19):5212-6. doi: 10.1016/j.bmcl.2006.07.009. Epub 2006 Jul 25. Bioorg Med Chem Lett. 2006. PMID: 16870439 Free PMC article.

7

Characterization of cell lines developed from the glassy-winged sharpshooter, Homalodisca coagulata (Hemiptera: Cicadellidae).

Kamita SG, Do ZN, Samra AI, Hagler JR, Hammock BD. Kamita SG, et al. Among authors: do zn. In Vitro Cell Dev Biol Anim. 2005 May-Jun;41(5-6):149-53. doi: 10.1290/0501002.1. In Vitro Cell Dev Biol Anim. 2005. PMID: 16153147

8

Structure-activity relationship for noncoplanar polychlorinated biphenyl congeners toward the ryanodine receptor-Ca2+ channel complex type 1 (RyR1).

Pessah IN, Hansen LG, Albertson TE, Garner CE, Ta TA, Do Z, Kim KH, Wong PW. Pessah IN, et al. Chem Res Toxicol. 2006 Jan;19(1):92-101. doi: 10.1021/tx050196m. Chem Res Toxicol. 2006. PMID: 16411661

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