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Becatecarin (rebeccamycin analog, NSC 655649) is a transport substrate and induces expression of the ATP-binding cassette transporter, ABCG2, in lung carcinoma cells.
Cancer Chemother Pharmacol. 2009 Aug;64(3):575-83. doi: 10.1007/s00280-008-0908-2. Epub 2009 Jan 9.
Cancer Chemother Pharmacol. 2009.
PMID: 19132374
Free PMC article.
Inhibition of ABCG2-mediated transport by protein kinase inhibitors with a bisindolylmaleimide or indolocarbazole structure.
Robey RW, Shukla S, Steadman K, Obrzut T, Finley EM, Ambudkar SV, Bates SE.
Robey RW, et al. Among authors: obrzut t.
Mol Cancer Ther. 2007 Jun;6(6):1877-85. doi: 10.1158/1535-7163.MCT-06-0811.
Mol Cancer Ther. 2007.
PMID: 17575116
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Laboratory correlates for a phase II trial of romidepsin in cutaneous and peripheral T-cell lymphoma.
Bates SE, Zhan Z, Steadman K, Obrzut T, Luchenko V, Frye R, Robey RW, Turner M, Gardner ER, Figg WD, Steinberg SM, Ling A, Fojo T, To KW, Piekarz RL.
Bates SE, et al. Among authors: obrzut t.
Br J Haematol. 2010 Jan;148(2):256-67. doi: 10.1111/j.1365-2141.2009.07954.x. Epub 2009 Oct 28.
Br J Haematol. 2010.
PMID: 19874311
Free PMC article.
Clinical Trial.
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Selective antimicrotubule activity of N1-phenyl-3,5-dinitro-N4,N4-di-n-propylsulfanilamide (GB-II-5) against kinetoplastid parasites.
Werbovetz KA, Sackett DL, Delfín D, Bhattacharya G, Salem M, Obrzut T, Rattendi D, Bacchi C.
Werbovetz KA, et al. Among authors: obrzut t.
Mol Pharmacol. 2003 Dec;64(6):1325-33. doi: 10.1124/mol.64.6.1325.
Mol Pharmacol. 2003.
PMID: 14645662
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