Guiducci C - Search Results

1

Signalling pathways leading to IFN-alpha production in human plasmacytoid dendritic cell and the possible use of agonists or antagonists of TLR7 and TLR9 in clinical indications.

Guiducci C, Coffman RL, Barrat FJ. Guiducci C, et al. J Intern Med. 2009 Jan;265(1):43-57. doi: 10.1111/j.1365-2796.2008.02050.x. J Intern Med. 2009. PMID: 19093959 Free article. Review.

2

Autoimmune skin inflammation is dependent on plasmacytoid dendritic cell activation by nucleic acids via TLR7 and TLR9.

Guiducci C, Tripodo C, Gong M, Sangaletti S, Colombo MP, Coffman RL, Barrat FJ. Guiducci C, et al. J Exp Med. 2010 Dec 20;207(13):2931-42. doi: 10.1084/jem.20101048. Epub 2010 Nov 29. J Exp Med. 2010. PMID: 21115693 Free PMC article.

3

Properties regulating the nature of the plasmacytoid dendritic cell response to Toll-like receptor 9 activation.

Guiducci C, Ott G, Chan JH, Damon E, Calacsan C, Matray T, Lee KD, Coffman RL, Barrat FJ. Guiducci C, et al. J Exp Med. 2006 Aug 7;203(8):1999-2008. doi: 10.1084/jem.20060401. Epub 2006 Jul 24. J Exp Med. 2006. PMID: 16864658 Free PMC article.

4

Treatment of lupus-prone mice with a dual inhibitor of TLR7 and TLR9 leads to reduction of autoantibody production and amelioration of disease symptoms.

Barrat FJ, Meeker T, Chan JH, Guiducci C, Coffman RL. Barrat FJ, et al. Among authors: guiducci c. Eur J Immunol. 2007 Dec;37(12):3582-6. doi: 10.1002/eji.200737815. Eur J Immunol. 2007. PMID: 18034431 Free article.

5

PI3K is critical for the nuclear translocation of IRF-7 and type I IFN production by human plasmacytoid predendritic cells in response to TLR activation.

Guiducci C, Ghirelli C, Marloie-Provost MA, Matray T, Coffman RL, Liu YJ, Barrat FJ, Soumelis V. Guiducci C, et al. J Exp Med. 2008 Feb 18;205(2):315-22. doi: 10.1084/jem.20070763. Epub 2008 Jan 28. J Exp Med. 2008. PMID: 18227218 Free PMC article.

6

TLR recognition of self nucleic acids hampers glucocorticoid activity in lupus.

Guiducci C, Gong M, Xu Z, Gill M, Chaussabel D, Meeker T, Chan JH, Wright T, Punaro M, Bolland S, Soumelis V, Banchereau J, Coffman RL, Pascual V, Barrat FJ. Guiducci C, et al. Nature. 2010 Jun 17;465(7300):937-41. doi: 10.1038/nature09102. Nature. 2010. PMID: 20559388 Free PMC article.

7

Netting neutrophils are major inducers of type I IFN production in pediatric systemic lupus erythematosus.

Garcia-Romo GS, Caielli S, Vega B, Connolly J, Allantaz F, Xu Z, Punaro M, Baisch J, Guiducci C, Coffman RL, Barrat FJ, Banchereau J, Pascual V. Garcia-Romo GS, et al. Among authors: guiducci c. Sci Transl Med. 2011 Mar 9;3(73):73ra20. doi: 10.1126/scitranslmed.3001201. Sci Transl Med. 2011. PMID: 21389264 Free PMC article.

8

Blocking TLR7- and TLR9-mediated IFN-α production by plasmacytoid dendritic cells does not diminish immune activation in early SIV infection.

Kader M, Smith AP, Guiducci C, Wonderlich ER, Normolle D, Watkins SC, Barrat FJ, Barratt-Boyes SM. Kader M, et al. Among authors: guiducci c. PLoS Pathog. 2013;9(7):e1003530. doi: 10.1371/journal.ppat.1003530. Epub 2013 Jul 25. PLoS Pathog. 2013. PMID: 23935491 Free PMC article.

9

RNA recognition by human TLR8 can lead to autoimmune inflammation.

Guiducci C, Gong M, Cepika AM, Xu Z, Tripodo C, Bennett L, Crain C, Quartier P, Cush JJ, Pascual V, Coffman RL, Barrat FJ. Guiducci C, et al. J Exp Med. 2013 Dec 16;210(13):2903-19. doi: 10.1084/jem.20131044. Epub 2013 Nov 25. J Exp Med. 2013. PMID: 24277153 Free PMC article.

10

Intratumoral injection of a CpG oligonucleotide reverts resistance to PD-1 blockade by expanding multifunctional CD8+ T cells.

Wang S, Campos J, Gallotta M, Gong M, Crain C, Naik E, Coffman RL, Guiducci C. Wang S, et al. Among authors: guiducci c. Proc Natl Acad Sci U S A. 2016 Nov 15;113(46):E7240-E7249. doi: 10.1073/pnas.1608555113. Epub 2016 Oct 31. Proc Natl Acad Sci U S A. 2016. PMID: 27799536 Free PMC article.

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