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Pharmacology of the pyrroloimidazole, SK&F 105809--I. Inhibition of inflammatory cytokine production and of 5-lipoxygenase- and cyclooxygenase-mediated metabolism of arachidonic acid.
Marshall PJ, Griswold DE, Breton J, Webb EF, Hillegass LM, Sarau HM, Newton J Jr, Lee JC, Bender PE, Hanna N. Marshall PJ, et al. Among authors: hillegass lm. Biochem Pharmacol. 1991 Jul 25;42(4):813-24. doi: 10.1016/0006-2952(91)90041-3. Biochem Pharmacol. 1991. PMID: 1907824
Pharmacology of the pyrroloimidazole, SK&F 105809--II. Antiinflammatory activity and inhibition of mediator production in vivo.
Griswold DE, Marshall PJ, Lee JC, Webb EF, Hillegass LM, Wartell J, Newton J Jr, Hanna N. Griswold DE, et al. Among authors: hillegass lm. Biochem Pharmacol. 1991 Jul 25;42(4):825-31. doi: 10.1016/0006-2952(91)90042-4. Biochem Pharmacol. 1991. PMID: 1907825
The biochemical evidence of inhibition of interleukin-1 (IL-1) production and 5-LO and CO activity, in vitro, by the metabolite (SK&F 105561) seen in the companion paper (Marshall PJ, Griswold DE, Breton J. Webb EF, Hillegass LM, Sarau HM, Newton J Jr, Lee JC, B …
The biochemical evidence of inhibition of interleukin-1 (IL-1) production and 5-LO and CO activity, in vitro, by the metabolite (SK&F 10 …
1-substituted 4-aryl-5-pyridinylimidazoles: a new class of cytokine suppressive drugs with low 5-lipoxygenase and cyclooxygenase inhibitory potency.
Boehm JC, Smietana JM, Sorenson ME, Garigipati RS, Gallagher TF, Sheldrake PL, Bradbeer J, Badger AM, Laydon JT, Lee JC, Hillegass LM, Griswold DE, Breton JJ, Chabot-Fletcher MC, Adams JL. Boehm JC, et al. Among authors: hillegass lm. J Med Chem. 1996 Sep 27;39(20):3929-37. doi: 10.1021/jm960415o. J Med Chem. 1996. PMID: 8831759
43 results