O'Toole SA - Search Results

1

BAG-1 predicts patient outcome and tamoxifen responsiveness in ER-positive invasive ductal carcinoma of the breast.

Millar EK, Anderson LR, McNeil CM, O'Toole SA, Pinese M, Crea P, Morey AL, Biankin AV, Henshall SM, Musgrove EA, Sutherland RL, Butt AJ. Millar EK, et al. Br J Cancer. 2009 Jan 13;100(1):123-33. doi: 10.1038/sj.bjc.6604809. Epub 2008 Dec 9. Br J Cancer. 2009. PMID: 19066611 Free PMC article.

2

Dysregulation of Hedgehog, Wnt and Notch signalling pathways in breast cancer.

Zardawi SJ, O'Toole SA, Sutherland RL, Musgrove EA. Zardawi SJ, et al. Histol Histopathol. 2009 Mar;24(3):385-98. doi: 10.14670/HH-24.385. Histol Histopathol. 2009. PMID: 19130408 Review.

3

The key hypoxia regulated gene CAIX is upregulated in basal-like breast tumours and is associated with resistance to chemotherapy.

Tan EY, Yan M, Campo L, Han C, Takano E, Turley H, Candiloro I, Pezzella F, Gatter KC, Millar EK, O'Toole SA, McNeil CM, Crea P, Segara D, Sutherland RL, Harris AL, Fox SB. Tan EY, et al. Br J Cancer. 2009 Jan 27;100(2):405-11. doi: 10.1038/sj.bjc.6604844. Br J Cancer. 2009. PMID: 19165203 Free PMC article.

4

Cyclin D1b protein expression in breast cancer is independent of cyclin D1a and associated with poor disease outcome.

Millar EK, Dean JL, McNeil CM, O'Toole SA, Henshall SM, Tran T, Lin J, Quong A, Comstock CE, Witkiewicz A, Musgrove EA, Rui H, Lemarchand L, Setiawan VW, Haiman CA, Knudsen KE, Sutherland RL, Knudsen ES. Millar EK, et al. Oncogene. 2009 Apr 16;28(15):1812-20. doi: 10.1038/onc.2009.13. Epub 2009 Mar 16. Oncogene. 2009. PMID: 19287456 Free PMC article.

5

The Hedgehog signalling pathway as a therapeutic target in early breast cancer development.

O'Toole SA, Swarbrick A, Sutherland RL. O'Toole SA, et al. Expert Opin Ther Targets. 2009 Sep;13(9):1095-103. doi: 10.1517/14728220903130612. Expert Opin Ther Targets. 2009. PMID: 19659449 Review.

6

Loss of STARD10 expression identifies a group of poor prognosis breast cancers independent of HER2/Neu and triple negative status.

Murphy NC, Biankin AV, Millar EK, McNeil CM, O'Toole SA, Segara D, Crea P, Olayioye MA, Lee CS, Fox SB, Morey AL, Christie M, Musgrove EA, Daly RJ, Lindeman GJ, Henshall SM, Visvader JE, Sutherland RL. Murphy NC, et al. Int J Cancer. 2010 Mar 15;126(6):1445-53. doi: 10.1002/ijc.24826. Int J Cancer. 2010. PMID: 19676041

7

PI3K pathway activation in breast cancer is associated with the basal-like phenotype and cancer-specific mortality.

López-Knowles E, O'Toole SA, McNeil CM, Millar EK, Qiu MR, Crea P, Daly RJ, Musgrove EA, Sutherland RL. López-Knowles E, et al. Int J Cancer. 2010 Mar 1;126(5):1121-31. doi: 10.1002/ijc.24831. Int J Cancer. 2010. PMID: 19685490

8

Prediction of local recurrence, distant metastases, and death after breast-conserving therapy in early-stage invasive breast cancer using a five-biomarker panel.

Millar EK, Graham PH, O'Toole SA, McNeil CM, Browne L, Morey AL, Eggleton S, Beretov J, Theocharous C, Capp A, Nasser E, Kearsley JH, Delaney G, Papadatos G, Fox C, Sutherland RL. Millar EK, et al. J Clin Oncol. 2009 Oct 1;27(28):4701-8. doi: 10.1200/JCO.2008.21.7075. Epub 2009 Aug 31. J Clin Oncol. 2009. PMID: 19720911 Clinical Trial.

9

Cytoplasmic localization of beta-catenin is a marker of poor outcome in breast cancer patients.

López-Knowles E, Zardawi SJ, McNeil CM, Millar EK, Crea P, Musgrove EA, Sutherland RL, O'Toole SA. López-Knowles E, et al. Cancer Epidemiol Biomarkers Prev. 2010 Jan;19(1):301-9. doi: 10.1158/1055-9965.EPI-09-0741. Cancer Epidemiol Biomarkers Prev. 2010. PMID: 20056651

10

Overexpression of the oncogenic signal transducer Gab2 occurs early in breast cancer development.

Fleuren ED, O'Toole S, Millar EK, McNeil C, Lopez-Knowles E, Boulghourjian A, Croucher DR, Schramek D, Brummer T, Penninger JM, Sutherland RL, Daly RJ. Fleuren ED, et al. Int J Cancer. 2010 Sep 1;127(6):1486-92. doi: 10.1002/ijc.25172. Int J Cancer. 2010. PMID: 20087860

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