Wagner K - Search Results

1

Soluble epoxide hydrolase and epoxyeicosatrienoic acids modulate two distinct analgesic pathways.

Inceoglu B, Jinks SL, Ulu A, Hegedus CM, Georgi K, Schmelzer KR, Wagner K, Jones PD, Morisseau C, Hammock BD. Inceoglu B, et al. Among authors: wagner k. Proc Natl Acad Sci U S A. 2008 Dec 2;105(48):18901-6. doi: 10.1073/pnas.0809765105. Epub 2008 Nov 21. Proc Natl Acad Sci U S A. 2008. PMID: 19028872 Free PMC article.

2

Epoxygenated fatty acids and soluble epoxide hydrolase inhibition: novel mediators of pain reduction.

Wagner K, Inceoglu B, Gill SS, Hammock BD. Wagner K, et al. J Agric Food Chem. 2011 Apr 13;59(7):2816-24. doi: 10.1021/jf102559q. Epub 2010 Oct 19. J Agric Food Chem. 2011. PMID: 20958046 Free PMC article.

3

Analgesia mediated by soluble epoxide hydrolase inhibitors is dependent on cAMP.

Inceoglu B, Wagner K, Schebb NH, Morisseau C, Jinks SL, Ulu A, Hegedus C, Rose T, Brosnan R, Hammock BD. Inceoglu B, et al. Among authors: wagner k. Proc Natl Acad Sci U S A. 2011 Mar 22;108(12):5093-7. doi: 10.1073/pnas.1101073108. Epub 2011 Mar 7. Proc Natl Acad Sci U S A. 2011. PMID: 21383170 Free PMC article.

4

Synthesis and structure-activity relationship studies of urea-containing pyrazoles as dual inhibitors of cyclooxygenase-2 and soluble epoxide hydrolase.

Hwang SH, Wagner KM, Morisseau C, Liu JY, Dong H, Wecksler AT, Hammock BD. Hwang SH, et al. J Med Chem. 2011 Apr 28;54(8):3037-50. doi: 10.1021/jm2001376. Epub 2011 Apr 5. J Med Chem. 2011. PMID: 21434686 Free PMC article.

5

Development of an ultra fast online-solid phase extraction (SPE) liquid chromatography electrospray tandem mass spectrometry (LC-ESI-MS/MS) based approach for the determination of drugs in pharmacokinetic studies.

Schebb NH, Inceoglu B, Rose T, Wagner K, Hammock BD. Schebb NH, et al. Among authors: wagner k. Anal Methods. 2011 Jan 1;3(2):420-428. doi: 10.1039/C0AY00714E. Anal Methods. 2011. PMID: 21660124 Free PMC article.

6

Soluble epoxide hydrolase inhibition, epoxygenated fatty acids and nociception.

Wagner K, Inceoglu B, Hammock BD. Wagner K, et al. Prostaglandins Other Lipid Mediat. 2011 Nov;96(1-4):76-83. doi: 10.1016/j.prostaglandins.2011.08.001. Epub 2011 Aug 10. Prostaglandins Other Lipid Mediat. 2011. PMID: 21854866 Free PMC article. Review.

7

Acute augmentation of epoxygenated fatty acid levels rapidly reduces pain-related behavior in a rat model of type I diabetes.

Inceoglu B, Wagner KM, Yang J, Bettaieb A, Schebb NH, Hwang SH, Morisseau C, Haj FG, Hammock BD. Inceoglu B, et al. Proc Natl Acad Sci U S A. 2012 Jul 10;109(28):11390-5. doi: 10.1073/pnas.1208708109. Epub 2012 Jun 25. Proc Natl Acad Sci U S A. 2012. PMID: 22733772 Free PMC article.

8

Comparative efficacy of 3 soluble epoxide hydrolase inhibitors in rat neuropathic and inflammatory pain models.

Wagner K, Inceoglu B, Dong H, Yang J, Hwang SH, Jones P, Morisseau C, Hammock BD. Wagner K, et al. Eur J Pharmacol. 2013 Jan 30;700(1-3):93-101. doi: 10.1016/j.ejphar.2012.12.015. Epub 2012 Dec 28. Eur J Pharmacol. 2013. PMID: 23276668 Free PMC article.

9

Rationally designed multitarget agents against inflammation and pain.

Hwang SH, Wecksler AT, Wagner K, Hammock BD. Hwang SH, et al. Among authors: wagner k. Curr Med Chem. 2013;20(13):1783-99. doi: 10.2174/0929867311320130013. Curr Med Chem. 2013. PMID: 23410172 Free PMC article. Review.

10

Epoxy fatty acids and inhibition of the soluble epoxide hydrolase selectively modulate GABA mediated neurotransmission to delay onset of seizures.

Inceoglu B, Zolkowska D, Yoo HJ, Wagner KM, Yang J, Hackett E, Hwang SH, Lee KS, Rogawski MA, Morisseau C, Hammock BD. Inceoglu B, et al. PLoS One. 2013 Dec 11;8(12):e80922. doi: 10.1371/journal.pone.0080922. eCollection 2013. PLoS One. 2013. PMID: 24349022 Free PMC article.

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