Simms L - Search Results

1

Mutation of ERBB2 provides a novel alternative mechanism for the ubiquitous activation of RAS-MAPK in ovarian serous low malignant potential tumors.

Anglesio MS, Arnold JM, George J, Tinker AV, Tothill R, Waddell N, Simms L, Locandro B, Fereday S, Traficante N, Russell P, Sharma R, Birrer MJ; AOCS Study Group; deFazio A, Chenevix-Trench G, Bowtell DD. Anglesio MS, et al. Among authors: simms l. Mol Cancer Res. 2008 Nov;6(11):1678-90. doi: 10.1158/1541-7786.MCR-08-0193. Mol Cancer Res. 2008. PMID: 19010816 Free PMC article.

2

No evidence for the H133Y mutation in SONIC HEDGEHOG in a collection of common tumour types.

Wicking C, Evans T, Henk B, Hayward N, Simms LA, Chenevix-Trench G, Pietsch T, Wainwright B. Wicking C, et al. Among authors: simms la. Oncogene. 1998 Feb 26;16(8):1091-3. doi: 10.1038/sj.onc.1201644. Oncogene. 1998. PMID: 9519883

3

Apparent protection from instability of repeat sequences in cancer-related genes in replication error positive gastrointestinal cancers.

Simms LA, Zou TT, Young J, Shi YQ, Lei J, Appel R, Rhyu MG, Sugimura H, Chenevix-Trench G, Souza RF, Meltzer SJ, Leggett BA. Simms LA, et al. Oncogene. 1997 May 29;14(21):2613-8. doi: 10.1038/sj.onc.1201094. Oncogene. 1997. PMID: 9191061

4

CDX2, a human homologue of Drosophila caudal, is mutated in both alleles in a replication error positive colorectal cancer.

Wicking C, Simms LA, Evans T, Walsh M, Chawengsaksophak K, Beck F, Chenevix-Trench G, Young J, Jass J, Leggett B, Wainwright B. Wicking C, et al. Among authors: simms la. Oncogene. 1998 Aug 6;17(5):657-9. doi: 10.1038/sj.onc.1201971. Oncogene. 1998. PMID: 9704932

5

Promoter hypermethylation frequency and BRAF mutations distinguish hereditary non-polyposis colon cancer from sporadic MSI-H colon cancer.

McGivern A, Wynter CV, Whitehall VL, Kambara T, Spring KJ, Walsh MD, Barker MA, Arnold S, Simms LA, Leggett BA, Young J, Jass JR. McGivern A, et al. Among authors: simms la. Fam Cancer. 2004;3(2):101-7. doi: 10.1023/B:FAME.0000039861.30651.c8. Fam Cancer. 2004. PMID: 15340260

6

Features of colorectal cancers with high-level microsatellite instability occurring in familial and sporadic settings: parallel pathways of tumorigenesis.

Young J, Simms LA, Biden KG, Wynter C, Whitehall V, Karamatic R, George J, Goldblatt J, Walpole I, Robin SA, Borten MM, Stitz R, Searle J, McKeone D, Fraser L, Purdie DR, Podger K, Price R, Buttenshaw R, Walsh MD, Barker M, Leggett BA, Jass JR. Young J, et al. Among authors: simms la. Am J Pathol. 2001 Dec;159(6):2107-16. doi: 10.1016/S0002-9440(10)63062-3. Am J Pathol. 2001. PMID: 11733361 Free PMC article.

7

BRAF mutation is associated with DNA methylation in serrated polyps and cancers of the colorectum.

Kambara T, Simms LA, Whitehall VL, Spring KJ, Wynter CV, Walsh MD, Barker MA, Arnold S, McGivern A, Matsubara N, Tanaka N, Higuchi T, Young J, Jass JR, Leggett BA. Kambara T, et al. Among authors: simms la. Gut. 2004 Aug;53(8):1137-44. doi: 10.1136/gut.2003.037671. Gut. 2004. PMID: 15247181 Free PMC article.

8

DNA microsatellite instability and mismatch repair protein loss in adenomas presenting in hereditary non-polyposis colorectal cancer.

Iino H, Simms L, Young J, Arnold J, Winship IM, Webb SI, Furlong KL, Leggett B, Jass JR. Iino H, et al. Among authors: simms l. Gut. 2000 Jul;47(1):37-42. doi: 10.1136/gut.47.1.37. Gut. 2000. PMID: 10861262 Free PMC article.

9

Reciprocal relationship between the tumor suppressors p53 and BAX in primary colorectal cancers.

Simms LA, Radford-Smith G, Biden KG, Buttenshaw R, Cummings M, Jass JR, Young J, Meltzer SJ, Leggett BA. Simms LA, et al. Oncogene. 1998 Oct 15;17(15):2003-8. doi: 10.1038/sj.onc.1202109. Oncogene. 1998. PMID: 9788444

10

Instabilotyping: comprehensive identification of frameshift mutations caused by coding region microsatellite instability.

Mori Y, Yin J, Rashid A, Leggett BA, Young J, Simms L, Kuehl PM, Langenberg P, Meltzer SJ, Stine OC. Mori Y, et al. Among authors: simms l. Cancer Res. 2001 Aug 15;61(16):6046-9. Cancer Res. 2001. PMID: 11507051

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