Importance of arginine 20 of the swine vesicular disease virus 2A protease for activity and virulence.
Inoue T, Alexandersen S, Clark AT, Murphy C, Quan M, Reid SM, Sakoda Y, Johns HL, Belsham GJ.
Inoue T, et al. Among authors: sakoda y.
J Virol. 2005 Jan;79(1):428-40. doi: 10.1128/JVI.79.1.428-440.2005.
J Virol. 2005.
PMID: 15596836
Free PMC article.
The 2A protease from an attenuated strain of SVDV (Ile at residue 20) is significantly defective at inducing cleavage of eIF4GI and the activation of IRES-dependent translation compared to the 2A protease from a pathogenic strain (J1/73, Arg at residue 20), but the two proteases …
The 2A protease from an attenuated strain of SVDV (Ile at residue 20) is significantly defective at inducing cleavage of eIF4GI and the acti …