Cox AG - Search Results

1

The thioredoxin reductase inhibitor auranofin triggers apoptosis through a Bax/Bak-dependent process that involves peroxiredoxin 3 oxidation.

Cox AG, Brown KK, Arner ES, Hampton MB. Cox AG, et al. Biochem Pharmacol. 2008 Oct 30;76(9):1097-109. doi: 10.1016/j.bcp.2008.08.021. Epub 2008 Aug 26. Biochem Pharmacol. 2008. PMID: 18789312

2

Bcl-2 over-expression promotes genomic instability by inhibiting apoptosis of cells exposed to hydrogen peroxide.

Cox AG, Hampton MB. Cox AG, et al. Carcinogenesis. 2007 Oct;28(10):2166-71. doi: 10.1093/carcin/bgm093. Epub 2007 Apr 13. Carcinogenesis. 2007. PMID: 17434928

3

Oxidation of mitochondrial peroxiredoxin 3 during the initiation of receptor-mediated apoptosis.

Cox AG, Pullar JM, Hughes G, Ledgerwood EC, Hampton MB. Cox AG, et al. Free Radic Biol Med. 2008 Mar 15;44(6):1001-9. doi: 10.1016/j.freeradbiomed.2007.11.017. Epub 2007 Dec 5. Free Radic Biol Med. 2008. PMID: 18164270

4

Inhibition of receptor-mediated apoptosis upon Bcl-2 overexpression is not associated with increased antioxidant status.

Thomson SJ, Cox AG, Cuddihy SL, Pullar JM, Hampton MB. Thomson SJ, et al. Among authors: cox ag. Biochem Biophys Res Commun. 2008 Oct 10;375(1):145-50. doi: 10.1016/j.bbrc.2008.07.133. Epub 2008 Aug 5. Biochem Biophys Res Commun. 2008. PMID: 18687309

5

Mitochondrial peroxiredoxin 3 is more resilient to hyperoxidation than cytoplasmic peroxiredoxins.

Cox AG, Pearson AG, Pullar JM, Jönsson TJ, Lowther WT, Winterbourn CC, Hampton MB. Cox AG, et al. Biochem J. 2009 Jun 12;421(1):51-8. doi: 10.1042/BJ20090242. Biochem J. 2009. PMID: 19356151 Free PMC article.

6

Redox potential and peroxide reactivity of human peroxiredoxin 3.

Cox AG, Peskin AV, Paton LN, Winterbourn CC, Hampton MB. Cox AG, et al. Biochemistry. 2009 Jul 14;48(27):6495-501. doi: 10.1021/bi900558g. Biochemistry. 2009. PMID: 19462976

7

Mitochondrial peroxiredoxin involvement in antioxidant defence and redox signalling.

Cox AG, Winterbourn CC, Hampton MB. Cox AG, et al. Biochem J. 2009 Dec 23;425(2):313-25. doi: 10.1042/BJ20091541. Biochem J. 2009. PMID: 20025614 Review.

8

Mitochondrial respiratory chain involvement in peroxiredoxin 3 oxidation by phenethyl isothiocyanate and auranofin.

Brown KK, Cox AG, Hampton MB. Brown KK, et al. Among authors: cox ag. FEBS Lett. 2010 Mar 19;584(6):1257-62. doi: 10.1016/j.febslet.2010.02.042. Epub 2010 Feb 19. FEBS Lett. 2010. PMID: 20176019 Free article.

9

Measuring the redox state of cellular peroxiredoxins by immunoblotting.

Cox AG, Winterbourn CC, Hampton MB. Cox AG, et al. Methods Enzymol. 2010;474:51-66. doi: 10.1016/S0076-6879(10)74004-0. Epub 2010 Jun 20. Methods Enzymol. 2010. PMID: 20609904

10

Removal of amino acid, peptide and protein hydroperoxides by reaction with peroxiredoxins 2 and 3.

Peskin AV, Cox AG, Nagy P, Morgan PE, Hampton MB, Davies MJ, Winterbourn CC. Peskin AV, et al. Among authors: cox ag. Biochem J. 2010 Dec 1;432(2):313-21. doi: 10.1042/BJ20101156. Biochem J. 2010. PMID: 20840079

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