Teplow DB - Search Results

1

Intramembrane proteolysis of GXGD-type aspartyl proteases is slowed by a familial Alzheimer disease-like mutation.

Fluhrer R, Fukumori A, Martin L, Grammer G, Haug-Kröper M, Klier B, Winkler E, Kremmer E, Condron MM, Teplow DB, Steiner H, Haass C. Fluhrer R, et al. Among authors: teplow db. J Biol Chem. 2008 Oct 31;283(44):30121-8. doi: 10.1074/jbc.M806092200. Epub 2008 Sep 3. J Biol Chem. 2008. PMID: 18768471 Free PMC article.

2

A gamma-secretase-like intramembrane cleavage of TNFalpha by the GxGD aspartyl protease SPPL2b.

Fluhrer R, Grammer G, Israel L, Condron MM, Haffner C, Friedmann E, Böhland C, Imhof A, Martoglio B, Teplow DB, Haass C. Fluhrer R, et al. Among authors: teplow db. Nat Cell Biol. 2006 Aug;8(8):894-6. doi: 10.1038/ncb1450. Epub 2006 Jul 9. Nat Cell Biol. 2006. PMID: 16829951

3

Effects of the English (H6R) and Tottori (D7N) familial Alzheimer disease mutations on amyloid beta-protein assembly and toxicity.

Ono K, Condron MM, Teplow DB. Ono K, et al. Among authors: teplow db. J Biol Chem. 2010 Jul 23;285(30):23186-97. doi: 10.1074/jbc.M109.086496. Epub 2010 May 7. J Biol Chem. 2010. PMID: 20452980 Free PMC article.

4

Apical sorting of beta-secretase limits amyloid beta-peptide production.

Capell A, Meyn L, Fluhrer R, Teplow DB, Walter J, Haass C. Capell A, et al. Among authors: teplow db. J Biol Chem. 2002 Feb 15;277(7):5637-43. doi: 10.1074/jbc.M109119200. Epub 2001 Dec 6. J Biol Chem. 2002. PMID: 11741885 Free article.

5

Kinetics of amyloid beta-protein degradation determined by novel fluorescence- and fluorescence polarization-based assays.

Leissring MA, Lu A, Condron MM, Teplow DB, Stein RL, Farris W, Selkoe DJ. Leissring MA, et al. Among authors: teplow db. J Biol Chem. 2003 Sep 26;278(39):37314-20. doi: 10.1074/jbc.M305627200. Epub 2003 Jul 16. J Biol Chem. 2003. PMID: 12867419 Free article.

6

The Tottori (D7N) and English (H6R) familial Alzheimer disease mutations accelerate Abeta fibril formation without increasing protofibril formation.

Hori Y, Hashimoto T, Wakutani Y, Urakami K, Nakashima K, Condron MM, Tsubuki S, Saido TC, Teplow DB, Iwatsubo T. Hori Y, et al. Among authors: teplow db. J Biol Chem. 2007 Feb 16;282(7):4916-4923. doi: 10.1074/jbc.M608220200. Epub 2006 Dec 14. J Biol Chem. 2007. PMID: 17170111 Free article.

7

Effects of grape seed-derived polyphenols on amyloid beta-protein self-assembly and cytotoxicity.

Ono K, Condron MM, Ho L, Wang J, Zhao W, Pasinetti GM, Teplow DB. Ono K, et al. Among authors: teplow db. J Biol Chem. 2008 Nov 21;283(47):32176-87. doi: 10.1074/jbc.M806154200. Epub 2008 Sep 24. J Biol Chem. 2008. PMID: 18815129 Free PMC article.

8

Amino acid position-specific contributions to amyloid beta-protein oligomerization.

Maji SK, Ogorzalek Loo RR, Inayathullah M, Spring SM, Vollers SS, Condron MM, Bitan G, Loo JA, Teplow DB. Maji SK, et al. Among authors: teplow db. J Biol Chem. 2009 Aug 28;284(35):23580-91. doi: 10.1074/jbc.M109.038133. Epub 2009 Jun 30. J Biol Chem. 2009. PMID: 19567875 Free PMC article.

9

A non-amyloidogenic function of BACE-2 in the secretory pathway.

Fluhrer R, Capell A, Westmeyer G, Willem M, Hartung B, Condron MM, Teplow DB, Haass C, Walter J. Fluhrer R, et al. Among authors: teplow db. J Neurochem. 2002 Jun;81(5):1011-20. doi: 10.1046/j.1471-4159.2002.00908.x. J Neurochem. 2002. PMID: 12065613 Free article.

10

Presenilin-dependent gamma-secretase processing of beta-amyloid precursor protein at a site corresponding to the S3 cleavage of Notch.

Sastre M, Steiner H, Fuchs K, Capell A, Multhaup G, Condron MM, Teplow DB, Haass C. Sastre M, et al. Among authors: teplow db. EMBO Rep. 2001 Sep;2(9):835-41. doi: 10.1093/embo-reports/kve180. Epub 2001 Aug 23. EMBO Rep. 2001. PMID: 11520861 Free PMC article.

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