Fluhrer R - Search Results

1

Intramembrane proteolysis of GXGD-type aspartyl proteases is slowed by a familial Alzheimer disease-like mutation.

Fluhrer R, Fukumori A, Martin L, Grammer G, Haug-Kröper M, Klier B, Winkler E, Kremmer E, Condron MM, Teplow DB, Steiner H, Haass C. Fluhrer R, et al. J Biol Chem. 2008 Oct 31;283(44):30121-8. doi: 10.1074/jbc.M806092200. Epub 2008 Sep 3. J Biol Chem. 2008. PMID: 18768471 Free PMC article.

2

Phosphorylation regulates intracellular trafficking of beta-secretase.

Walter J, Fluhrer R, Hartung B, Willem M, Kaether C, Capell A, Lammich S, Multhaup G, Haass C. Walter J, et al. Among authors: fluhrer r. J Biol Chem. 2001 May 4;276(18):14634-41. doi: 10.1074/jbc.M011116200. Epub 2001 Jan 29. J Biol Chem. 2001. PMID: 11278841 Free article.

3

Apical sorting of beta-secretase limits amyloid beta-peptide production.

Capell A, Meyn L, Fluhrer R, Teplow DB, Walter J, Haass C. Capell A, et al. Among authors: fluhrer r. J Biol Chem. 2002 Feb 15;277(7):5637-43. doi: 10.1074/jbc.M109119200. Epub 2001 Dec 6. J Biol Chem. 2002. PMID: 11741885 Free article.

4

A non-amyloidogenic function of BACE-2 in the secretory pathway.

Fluhrer R, Capell A, Westmeyer G, Willem M, Hartung B, Condron MM, Teplow DB, Haass C, Walter J. Fluhrer R, et al. J Neurochem. 2002 Jun;81(5):1011-20. doi: 10.1046/j.1471-4159.2002.00908.x. J Neurochem. 2002. PMID: 12065613 Free article.

5

Identification of a beta-secretase activity, which truncates amyloid beta-peptide after its presenilin-dependent generation.

Fluhrer R, Multhaup G, Schlicksupp A, Okochi M, Takeda M, Lammich S, Willem M, Westmeyer G, Bode W, Walter J, Haass C. Fluhrer R, et al. J Biol Chem. 2003 Feb 21;278(8):5531-8. doi: 10.1074/jbc.M211485200. Epub 2002 Dec 5. J Biol Chem. 2003. PMID: 12471021 Free article.

6

Phosphorylation of presenilin 1 at the caspase recognition site regulates its proteolytic processing and the progression of apoptosis.

Fluhrer R, Friedlein A, Haass C, Walter J. Fluhrer R, et al. J Biol Chem. 2004 Jan 16;279(3):1585-93. doi: 10.1074/jbc.M306653200. Epub 2003 Oct 22. J Biol Chem. 2004. PMID: 14576165 Free article.

7

Differential localization and identification of a critical aspartate suggest non-redundant proteolytic functions of the presenilin homologues SPPL2b and SPPL3.

Krawitz P, Haffner C, Fluhrer R, Steiner H, Schmid B, Haass C. Krawitz P, et al. Among authors: fluhrer r. J Biol Chem. 2005 Nov 25;280(47):39515-23. doi: 10.1074/jbc.M501645200. Epub 2005 Jul 5. J Biol Chem. 2005. PMID: 15998642 Free article.

8

A gamma-secretase-like intramembrane cleavage of TNFalpha by the GxGD aspartyl protease SPPL2b.

Fluhrer R, Grammer G, Israel L, Condron MM, Haffner C, Friedmann E, Böhland C, Imhof A, Martoglio B, Teplow DB, Haass C. Fluhrer R, et al. Nat Cell Biol. 2006 Aug;8(8):894-6. doi: 10.1038/ncb1450. Epub 2006 Jul 9. Nat Cell Biol. 2006. PMID: 16829951

9

A structural switch of presenilin 1 by glycogen synthase kinase 3beta-mediated phosphorylation regulates the interaction with beta-catenin and its nuclear signaling.

Prager K, Wang-Eckhardt L, Fluhrer R, Killick R, Barth E, Hampel H, Haass C, Walter J. Prager K, et al. Among authors: fluhrer r. J Biol Chem. 2007 May 11;282(19):14083-93. doi: 10.1074/jbc.M608437200. Epub 2007 Mar 14. J Biol Chem. 2007. PMID: 17360711 Free article.

10

Signal peptide peptidases and gamma-secretase: cousins of the same protease family?

Fluhrer R, Haass C. Fluhrer R, et al. Neurodegener Dis. 2007;4(2-3):112-6. doi: 10.1159/000101835. Neurodegener Dis. 2007. PMID: 17596705 Free article. Review.

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

51 results

Search Page

Filters