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Fenofibric acid, an active form of fenofibrate, increases apolipoprotein A-I-mediated high-density lipoprotein biogenesis by enhancing transcription of ATP-binding cassette transporter A1 gene in a liver X receptor-dependent manner.
Arakawa R, Tamehiro N, Nishimaki-Mogami T, Ueda K, Yokoyama S. Arakawa R, et al. Arterioscler Thromb Vasc Biol. 2005 Jun;25(6):1193-7. doi: 10.1161/01.ATV.0000163844.07815.c4. Epub 2005 Mar 24. Arterioscler Thromb Vasc Biol. 2005. PMID: 15790930
HX531, a retinoid X receptor antagonist, inhibited the 9-cis retinoic acid-induced binding with steroid receptor coactivator-1 as detected by surface plasmon resonance.
Kanayasu-Toyoda T, Fujino T, Oshizawa T, Suzuki T, Nishimaki-Mogami T, Sato Y, Sawada J, Inoue K, Shudo K, Ohno Y, Yamaguchi T. Kanayasu-Toyoda T, et al. J Steroid Biochem Mol Biol. 2005 Mar;94(4):303-9. doi: 10.1016/j.jsbmb.2004.11.007. Epub 2005 Feb 1. J Steroid Biochem Mol Biol. 2005. PMID: 15857749
5Alpha-bile alcohols function as farnesoid X receptor antagonists.
Nishimaki-Mogami T, Kawahara Y, Tamehiro N, Yoshida T, Inoue K, Ohno Y, Nagao T, Une M. Nishimaki-Mogami T, et al. Biochem Biophys Res Commun. 2006 Jan 6;339(1):386-91. doi: 10.1016/j.bbrc.2005.11.027. Epub 2005 Nov 14. Biochem Biophys Res Commun. 2006. PMID: 16300737
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