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CHEK2 mutations affecting kinase activity together with mutations in TP53 indicate a functional pathway associated with resistance to epirubicin in primary breast cancer.
Chrisanthar R, Knappskog S, Løkkevik E, Anker G, Østenstad B, Lundgren S, Berge EO, Risberg T, Mjaaland I, Maehle L, Engebretsen LF, Lillehaug JR, Lønning PE. Chrisanthar R, et al. Among authors: lillehaug jr. PLoS One. 2008 Aug 26;3(8):e3062. doi: 10.1371/journal.pone.0003062. PLoS One. 2008. PMID: 18725978 Free PMC article.
The novel p21 polymorphism p21G251A is associated with locally advanced breast cancer.
Staalesen V, Knappskog S, Chrisanthar R, Nordgard SH, Løkkevik E, Anker G, Ostenstad B, Lundgren S, Risberg T, Mjaaland I, Gram IT, Kristensen VN, Børresen-Dale AL, Lillehaug JR, Lønning PE. Staalesen V, et al. Among authors: lillehaug jr. Clin Cancer Res. 2006 Oct 15;12(20 Pt 1):6000-4. doi: 10.1158/1078-0432.CCR-05-2822. Clin Cancer Res. 2006. PMID: 17062672
Mutations and polymorphisms of the p21B transcript in breast cancer.
Knappskog S, Chrisanthar R, Staalesen V, Børresen-Dale AL, Gram IT, Lillehaug JR, Lønning PE. Knappskog S, et al. Among authors: lillehaug jr. Int J Cancer. 2007 Aug 15;121(4):908-10. doi: 10.1002/ijc.22777. Int J Cancer. 2007. PMID: 17443496
Alterations of the retinoblastoma gene in metastatic breast cancer.
Berge EO, Knappskog S, Lillehaug JR, Lønning PE. Berge EO, et al. Among authors: lillehaug jr. Clin Exp Metastasis. 2011 Mar;28(3):319-26. doi: 10.1007/s10585-011-9375-y. Epub 2011 Jan 21. Clin Exp Metastasis. 2011. PMID: 21253829 Free PMC article.
Predictive and prognostic impact of TP53 mutations and MDM2 promoter genotype in primary breast cancer patients treated with epirubicin or paclitaxel.
Chrisanthar R, Knappskog S, Løkkevik E, Anker G, Ostenstad B, Lundgren S, Risberg T, Mjaaland I, Skjønsberg G, Aas T, Schlichting E, Fjösne HE, Nysted A, Lillehaug JR, Lønning PE. Chrisanthar R, et al. Among authors: lillehaug jr. PLoS One. 2011 Apr 27;6(4):e19249. doi: 10.1371/journal.pone.0019249. PLoS One. 2011. PMID: 21556366 Free PMC article. Clinical Trial.
148 results