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TRPP2 and TRPV4 form a polymodal sensory channel complex.
Köttgen M, Buchholz B, Garcia-Gonzalez MA, Kotsis F, Fu X, Doerken M, Boehlke C, Steffl D, Tauber R, Wegierski T, Nitschke R, Suzuki M, Kramer-Zucker A, Germino GG, Watnick T, Prenen J, Nilius B, Kuehn EW, Walz G. Köttgen M, et al. Among authors: walz g. J Cell Biol. 2008 Aug 11;182(3):437-47. doi: 10.1083/jcb.200805124. J Cell Biol. 2008. PMID: 18695040 Free PMC article.
Interaction with podocin facilitates nephrin signaling.
Huber TB, Kottgen M, Schilling B, Walz G, Benzing T. Huber TB, et al. Among authors: walz g. J Biol Chem. 2001 Nov 9;276(45):41543-6. doi: 10.1074/jbc.C100452200. Epub 2001 Sep 18. J Biol Chem. 2001. PMID: 11562357 Free article.
Trafficking of TRPP2 by PACS proteins represents a novel mechanism of ion channel regulation.
Köttgen M, Benzing T, Simmen T, Tauber R, Buchholz B, Feliciangeli S, Huber TB, Schermer B, Kramer-Zucker A, Höpker K, Simmen KC, Tschucke CC, Sandford R, Kim E, Thomas G, Walz G. Köttgen M, et al. Among authors: walz g. EMBO J. 2005 Feb 23;24(4):705-16. doi: 10.1038/sj.emboj.7600566. Epub 2005 Feb 3. EMBO J. 2005. PMID: 15692563 Free PMC article.
Subcellular localization and trafficking of polycystins.
Köttgen M, Walz G. Köttgen M, et al. Among authors: walz g. Pflugers Arch. 2005 Oct;451(1):286-93. doi: 10.1007/s00424-005-1417-3. Epub 2005 May 14. Pflugers Arch. 2005. PMID: 15895248 Review.
Phosphorylation by casein kinase 2 induces PACS-1 binding of nephrocystin and targeting to cilia.
Schermer B, Höpker K, Omran H, Ghenoiu C, Fliegauf M, Fekete A, Horvath J, Köttgen M, Hackl M, Zschiedrich S, Huber TB, Kramer-Zucker A, Zentgraf H, Blaukat A, Walz G, Benzing T. Schermer B, et al. Among authors: walz g. EMBO J. 2005 Dec 21;24(24):4415-24. doi: 10.1038/sj.emboj.7600885. Epub 2005 Nov 24. EMBO J. 2005. PMID: 16308564 Free PMC article.
The mTOR pathway is regulated by polycystin-1, and its inhibition reverses renal cystogenesis in polycystic kidney disease.
Shillingford JM, Murcia NS, Larson CH, Low SH, Hedgepeth R, Brown N, Flask CA, Novick AC, Goldfarb DA, Kramer-Zucker A, Walz G, Piontek KB, Germino GG, Weimbs T. Shillingford JM, et al. Among authors: walz g. Proc Natl Acad Sci U S A. 2006 Apr 4;103(14):5466-71. doi: 10.1073/pnas.0509694103. Epub 2006 Mar 27. Proc Natl Acad Sci U S A. 2006. PMID: 16567633 Free PMC article.
304 results