Horn S - Search Results

1

Steelman LS, Stadelman KM, Chappell WH, Horn S, Bäsecke J, Cervello M, Nicoletti F, Libra M, Stivala F, Martelli AM, McCubrey JA. Steelman LS, et al. Among authors: horn s. Expert Opin Ther Targets. 2008 Sep;12(9):1139-65. doi: 10.1517/14728222.12.9.1139. Expert Opin Ther Targets. 2008. PMID: 18694380 Review.

2

Mutations in the catalytic subunit of class IA PI3K confer leukemogenic potential to hematopoietic cells.

Horn S, Bergholz U, Jücker M, McCubrey JA, Trümper L, Stocking C, Bäsecke J. Horn S, et al. Oncogene. 2008 Jul 3;27(29):4096-106. doi: 10.1038/onc.2008.40. Epub 2008 Mar 3. Oncogene. 2008. PMID: 18317450

3

Alteration of Akt activity increases chemotherapeutic drug and hormonal resistance in breast cancer yet confers an achilles heel by sensitization to targeted therapy.

McCubrey JA, Sokolosky ML, Lehmann BD, Taylor JR, Navolanic PM, Chappell WH, Abrams SL, Stadelman KM, Wong EW, Misaghian N, Horn S, Bäsecke J, Libra M, Stivala F, Ligresti G, Tafuri A, Milella M, Zarzycki M, Dzugaj A, Chiarini F, Evangelisti C, Martelli AM, Terrian DM, Franklin RA, Steelman LS. McCubrey JA, et al. Among authors: horn s. Adv Enzyme Regul. 2008;48:113-35. doi: 10.1016/j.advenzreg.2008.02.006. Epub 2008 Feb 21. Adv Enzyme Regul. 2008. PMID: 18423407 Free PMC article.

4

PKR activity is required for acute leukemic cell maintenance and growth: a role for PKR-mediated phosphatase activity to regulate GSK-3 phosphorylation.

Blalock WL, Grimaldi C, Fala F, Follo M, Horn S, Basecke J, Martinelli G, Cocco L, Martelli AM. Blalock WL, et al. Among authors: horn s. J Cell Physiol. 2009 Oct;221(1):232-41. doi: 10.1002/jcp.21848. J Cell Physiol. 2009. PMID: 19507191

5

Erucylphosphohomocholine, the first intravenously applicable alkylphosphocholine, is cytotoxic to acute myelogenous leukemia cells through JNK- and PP2A-dependent mechanisms.

Martelli AM, Papa V, Tazzari PL, Ricci F, Evangelisti C, Chiarini F, Grimaldi C, Cappellini A, Martinelli G, Ottaviani E, Pagliaro P, Horn S, Bäsecke J, Lindner LH, Eibl H, McCubrey JA. Martelli AM, et al. Among authors: horn s. Leukemia. 2010 Apr;24(4):687-98. doi: 10.1038/leu.2010.32. Epub 2010 Mar 4. Leukemia. 2010. PMID: 20200557

6

Ikaros sets the threshold for negative B-cell selection by regulation of the signaling strength of the AKT pathway.

Ehm PAH, Horn S, Hoffer K, Kriegs M, Horn M, Giehler S, Nalaskowski M, Rehbach C, Horstmann MA, Jücker M. Ehm PAH, et al. Among authors: horn m, horn s. Cell Commun Signal. 2024 Jul 12;22(1):360. doi: 10.1186/s12964-024-01732-5. Cell Commun Signal. 2024. PMID: 38992657 Free PMC article.

7

The inositol 5-phosphatase SHIP is expressed as 145 and 135 kDa proteins in blood and bone marrow cells in vivo, whereas carboxyl-truncated forms of SHIP are generated by proteolytic cleavage in vitro.

Horn S, Meyer J, Heukeshoven J, Fehse B, Schulze C, Li S, Frey J, Poll S, Stocking C, Jücker M. Horn S, et al. Leukemia. 2001 Jan;15(1):112-20. doi: 10.1038/sj.leu.2401990. Leukemia. 2001. PMID: 11243378

8

Expression of a mutated form of the p85alpha regulatory subunit of phosphatidylinositol 3-kinase in a Hodgkin's lymphoma-derived cell line (CO).

Jücker M, Südel K, Horn S, Sickel M, Wegner W, Fiedler W, Feldman RA. Jücker M, et al. Among authors: horn s. Leukemia. 2002 May;16(5):894-901. doi: 10.1038/sj.leu.2402484. Leukemia. 2002. PMID: 11986952

9

An increase in the expression and total activity of endogenous p60(c-Src) in several factor-independent mutants of a human GM-CSF-dependent leukemia cell line (TF-1).

Horn S, Meyer J, Stocking C, Ostertag W, Jücker M. Horn S, et al. Oncogene. 2003 Oct 16;22(46):7170-80. doi: 10.1038/sj.onc.1206856. Oncogene. 2003. PMID: 14562045

10

Restoration of SHIP activity in a human leukemia cell line downregulates constitutively activated phosphatidylinositol 3-kinase/Akt/GSK-3beta signaling and leads to an increased transit time through the G1 phase of the cell cycle.

Horn S, Endl E, Fehse B, Weck MM, Mayr GW, Jücker M. Horn S, et al. Leukemia. 2004 Nov;18(11):1839-49. doi: 10.1038/sj.leu.2403529. Leukemia. 2004. PMID: 15457186

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