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The Cytochrome P450 Slow Metabolizers CYP2C9*2 and CYP2C9*3 Directly Regulate Tumorigenesis via Reduced Epoxyeicosatrienoic Acid Production.
Sausville LN, Gangadhariah MH, Chiusa M, Mei S, Wei S, Zent R, Luther JM, Shuey MM, Capdevila JH, Falck JR, Guengerich FP, Williams SM, Pozzi A. Sausville LN, et al. Among authors: wei s. Cancer Res. 2018 Sep 1;78(17):4865-4877. doi: 10.1158/0008-5472.CAN-17-3977. Epub 2018 Jul 16. Cancer Res. 2018. PMID: 30012669 Free PMC article.
PPARα activation can help prevent and treat non-small cell lung cancer.
Skrypnyk N, Chen X, Hu W, Su Y, Mont S, Yang S, Gangadhariah M, Wei S, Falck JR, Jat JL, Zent R, Capdevila JH, Pozzi A. Skrypnyk N, et al. Among authors: wei s. Cancer Res. 2014 Jan 15;74(2):621-31. doi: 10.1158/0008-5472.CAN-13-1928. Epub 2013 Dec 3. Cancer Res. 2014. PMID: 24302581 Free PMC article.
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