Inuzuka H - Search Results

1

Experimental approaches to investigate the proteasomal degradation pathways involved in regulation of apoptosis.

Tseng A, Inuzuka H, Gao D, Singh A, Wei W. Tseng A, et al. Among authors: inuzuka h. Methods Enzymol. 2008;446:205-23. doi: 10.1016/S0076-6879(08)01612-1. Methods Enzymol. 2008. PMID: 18603124

2

Phosphorylation by Akt1 promotes cytoplasmic localization of Skp2 and impairs APCCdh1-mediated Skp2 destruction.

Gao D, Inuzuka H, Tseng A, Chin RY, Toker A, Wei W. Gao D, et al. Among authors: inuzuka h. Nat Cell Biol. 2009 Apr;11(4):397-408. doi: 10.1038/ncb1847. Epub 2009 Mar 8. Nat Cell Biol. 2009. PMID: 19270695 Free PMC article.

3

Cdh1 regulates cell cycle through modulating the claspin/Chk1 and the Rb/E2F1 pathways.

Gao D, Inuzuka H, Korenjak M, Tseng A, Wu T, Wan L, Kirschner M, Dyson N, Wei W. Gao D, et al. Among authors: inuzuka h. Mol Biol Cell. 2009 Jul;20(14):3305-16. doi: 10.1091/mbc.e09-01-0092. Epub 2009 May 28. Mol Biol Cell. 2009. PMID: 19477924 Free PMC article.

4

Akt finds its new path to regulate cell cycle through modulating Skp2 activity and its destruction by APC/Cdh1.

Gao D, Inuzuka H, Tseng A, Wei W. Gao D, et al. Among authors: inuzuka h. Cell Div. 2009 Jun 23;4:11. doi: 10.1186/1747-1028-4-11. Cell Div. 2009. PMID: 19549334 Free PMC article.

5

Phosphorylation by casein kinase I promotes the turnover of the Mdm2 oncoprotein via the SCF(beta-TRCP) ubiquitin ligase.

Inuzuka H, Tseng A, Gao D, Zhai B, Zhang Q, Shaik S, Wan L, Ang XL, Mock C, Yin H, Stommel JM, Gygi S, Lahav G, Asara J, Xiao ZX, Kaelin WG Jr, Harper JW, Wei W. Inuzuka H, et al. Cancer Cell. 2010 Aug 9;18(2):147-59. doi: 10.1016/j.ccr.2010.06.015. Cancer Cell. 2010. PMID: 20708156 Free PMC article.

6

Rictor forms a complex with Cullin-1 to promote SGK1 ubiquitination and destruction.

Gao D, Wan L, Inuzuka H, Berg AH, Tseng A, Zhai B, Shaik S, Bennett E, Tron AE, Gasser JA, Lau A, Gygi SP, Harper JW, DeCaprio JA, Toker A, Wei W. Gao D, et al. Among authors: inuzuka h. Mol Cell. 2010 Sep 10;39(5):797-808. doi: 10.1016/j.molcel.2010.08.016. Mol Cell. 2010. PMID: 20832730 Free PMC article.

7

Novel insights into the molecular mechanisms governing Mdm2 ubiquitination and destruction.

Inuzuka H, Fukushima H, Shaik S, Wei W. Inuzuka H, et al. Oncotarget. 2010 Nov;1(7):685-690. doi: 10.18632/oncotarget.202. Oncotarget. 2010. PMID: 21317463 Free PMC article. Review.

8

SCF(FBW7) regulates cellular apoptosis by targeting MCL1 for ubiquitylation and destruction.

Inuzuka H, Shaik S, Onoyama I, Gao D, Tseng A, Maser RS, Zhai B, Wan L, Gutierrez A, Lau AW, Xiao Y, Christie AL, Aster J, Settleman J, Gygi SP, Kung AL, Look T, Nakayama KI, DePinho RA, Wei W. Inuzuka H, et al. Nature. 2011 Mar 3;471(7336):104-9. doi: 10.1038/nature09732. Nature. 2011. PMID: 21368833 Free PMC article.

9

Mcl-1 ubiquitination and destruction.

Inuzuka H, Fukushima H, Shaik S, Liu P, Lau AW, Wei W. Inuzuka H, et al. Oncotarget. 2011 Mar;2(3):239-44. doi: 10.18632/oncotarget.242. Oncotarget. 2011. PMID: 21608150 Free PMC article. Review.

10

Skp2: a novel potential therapeutic target for prostate cancer.

Wang Z, Gao D, Fukushima H, Inuzuka H, Liu P, Wan L, Sarkar FH, Wei W. Wang Z, et al. Among authors: inuzuka h. Biochim Biophys Acta. 2012 Jan;1825(1):11-7. doi: 10.1016/j.bbcan.2011.09.002. Epub 2011 Sep 22. Biochim Biophys Acta. 2012. PMID: 21963805 Free PMC article. Review.

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