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Cigarette smoke-induced neurogenic inflammation is mediated by alpha,beta-unsaturated aldehydes and the TRPA1 receptor in rodents.
Andrè E, Campi B, Materazzi S, Trevisani M, Amadesi S, Massi D, Creminon C, Vaksman N, Nassini R, Civelli M, Baraldi PG, Poole DP, Bunnett NW, Geppetti P, Patacchini R. Andrè E, et al. Among authors: baraldi pg. J Clin Invest. 2008 Jul;118(7):2574-82. doi: 10.1172/JCI34886. J Clin Invest. 2008. PMID: 18568077 Free PMC article.
7-Substituted-pyrrolo[3,2-d]pyrimidine-2,4-dione derivatives as antagonists of the transient receptor potential ankyrin 1 (TRPA1) channel: a promising approach for treating pain and inflammation.
Baraldi PG, Romagnoli R, Saponaro G, Aghazadeh Tabrizi M, Baraldi S, Pedretti P, Fusi C, Nassini R, Materazzi S, Geppetti P, Preti D. Baraldi PG, et al. Among authors: baraldi s. Bioorg Med Chem. 2012 Mar 1;20(5):1690-8. doi: 10.1016/j.bmc.2012.01.020. Epub 2012 Jan 24. Bioorg Med Chem. 2012. PMID: 22325155
Allosteric enhancers for A1 adenosine receptor.
Baraldi PG, Iaconinoto MA, Moorman AR, Carrion MD, Cara CL, Preti D, López OC, Fruttarolo F, Tabrizi MA, Romagnoli R. Baraldi PG, et al. Mini Rev Med Chem. 2007 Jun;7(6):559-69. doi: 10.2174/138955707780859459. Mini Rev Med Chem. 2007. PMID: 17584155 Review.
The P2X7 receptor as a therapeutic target.
Romagnoli R, Baraldi PG, Cruz-Lopez O, Lopez-Cara C, Preti D, Borea PA, Gessi S. Romagnoli R, et al. Among authors: baraldi pg. Expert Opin Ther Targets. 2008 May;12(5):647-61. doi: 10.1517/14728222.12.5.647. Expert Opin Ther Targets. 2008. PMID: 18410246 Review.
247 results