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"Click" saccharide/beta-lactam hybrids for lectin inhibition.
Palomo C, Aizpurua JM, Balentová E, Azcune I, Santos JI, Jiménez-Barbero J, Cañada J, Miranda JI. Palomo C, et al. Org Lett. 2008 Jun 5;10(11):2227-30. doi: 10.1021/ol8006259. Epub 2008 May 9. Org Lett. 2008. PMID: 18465871
A simple structural-based approach to prevent aminoglycoside inactivation by bacterial defense proteins. Conformational restriction provides effective protection against neomycin-B nucleotidylation by ANT4.
Asensio JL, Hidalgo A, Bastida A, Torrado M, Corzana F, Chiara JL, García-Junceda E, Cañada J, Jiménez-Barbero J. Asensio JL, et al. J Am Chem Soc. 2005 Jun 15;127(23):8278-9. doi: 10.1021/ja051722z. J Am Chem Soc. 2005. PMID: 15941249 Free article.
518 results