Arruda VR - Search Results

1

Safety and efficacy of regional intravenous (r.i.) versus intramuscular (i.m.) delivery of rAAV1 and rAAV8 to nonhuman primate skeletal muscle.

Toromanoff A, Chérel Y, Guilbaud M, Penaud-Budloo M, Snyder RO, Haskins ME, Deschamps JY, Guigand L, Podevin G, Arruda VR, High KA, Stedman HH, Rolling F, Anegon I, Moullier P, Le Guiner C. Toromanoff A, et al. Among authors: arruda vr. Mol Ther. 2008 Jul;16(7):1291-9. doi: 10.1038/mt.2008.87. Epub 2008 May 6. Mol Ther. 2008. PMID: 18461055 Free article.

2

Safety and Efficacy of Regional Intravenous (RI) Versus Intramuscular (IM) Delivery of rAAV1 and rAAV8 to Nonhuman Primate Skeletal Muscle.

Toromanoff A, Chérel Y, Guilbaud M, Penaud-Budloo M, Snyder RO, Haskins ME, Deschamps JY, Guigand L, Podevin G, Arruda VR, High KA, Stedman HH, Rolling F, Anegon I, Moullier P, Le Guiner C. Toromanoff A, et al. Among authors: arruda vr. Mol Ther. 2008 Jul;16(7):1291-1299. doi: 10.1038/mt.2008.87. Epub 2016 Dec 8. Mol Ther. 2008. PMID: 28178483

3

Regional intravascular delivery of AAV-2-F.IX to skeletal muscle achieves long-term correction of hemophilia B in a large animal model.

Arruda VR, Stedman HH, Nichols TC, Haskins ME, Nicholson M, Herzog RW, Couto LB, High KA. Arruda VR, et al. Blood. 2005 May 1;105(9):3458-64. doi: 10.1182/blood-2004-07-2908. Epub 2004 Oct 12. Blood. 2005. PMID: 15479726 Free PMC article.

4

Evidence of multiyear factor IX expression by AAV-mediated gene transfer to skeletal muscle in an individual with severe hemophilia B.

Jiang H, Pierce GF, Ozelo MC, de Paula EV, Vargas JA, Smith P, Sommer J, Luk A, Manno CS, High KA, Arruda VR. Jiang H, et al. Among authors: arruda vr. Mol Ther. 2006 Sep;14(3):452-5. doi: 10.1016/j.ymthe.2006.05.004. Epub 2006 Jul 5. Mol Ther. 2006. PMID: 16822719 Free article. Clinical Trial.

5

Safety of AAV factor IX peripheral transvenular gene delivery to muscle in hemophilia B dogs.

Haurigot V, Mingozzi F, Buchlis G, Hui DJ, Chen Y, Basner-Tschakarjan E, Arruda VR, Radu A, Franck HG, Wright JF, Zhou S, Stedman HH, Bellinger DA, Nichols TC, High KA. Haurigot V, et al. Among authors: arruda vr. Mol Ther. 2010 Jul;18(7):1318-29. doi: 10.1038/mt.2010.73. Epub 2010 Apr 27. Mol Ther. 2010. PMID: 20424599 Free PMC article.

6

Safety of liver gene transfer following peripheral intravascular delivery of adeno-associated virus (AAV)-5 and AAV-6 in a large animal model.

Favaro P, Finn JD, Siner JI, Wright JF, High KA, Arruda VR. Favaro P, et al. Among authors: arruda vr. Hum Gene Ther. 2011 Jul;22(7):843-52. doi: 10.1089/hum.2010.155. Epub 2011 Mar 8. Hum Gene Ther. 2011. PMID: 21126217 Free PMC article.

7

Biodistribution and shedding of AAV vectors.

Le Guiner C, Moullier P, Arruda VR. Le Guiner C, et al. Among authors: arruda vr. Methods Mol Biol. 2011;807:339-59. doi: 10.1007/978-1-61779-370-7_15. Methods Mol Biol. 2011. PMID: 22034038

8

Translational data from adeno-associated virus-mediated gene therapy of hemophilia B in dogs.

Nichols TC, Whitford MH, Arruda VR, Stedman HH, Kay MA, High KA. Nichols TC, et al. Among authors: arruda vr. Hum Gene Ther Clin Dev. 2015 Mar;26(1):5-14. doi: 10.1089/humc.2014.153. Epub 2015 Feb 12. Hum Gene Ther Clin Dev. 2015. PMID: 25675273 Free PMC article. Review.

9

Host and vector-dependent effects on the risk of germline transmission of AAV vectors.

Favaro P, Downey HD, Zhou JS, Wright JF, Hauck B, Mingozzi F, High KA, Arruda VR. Favaro P, et al. Among authors: arruda vr. Mol Ther. 2009 Jun;17(6):1022-30. doi: 10.1038/mt.2009.56. Epub 2009 Mar 17. Mol Ther. 2009. PMID: 19293773 Free PMC article.

10

Peripheral transvenular delivery of adeno-associated viral vectors to skeletal muscle as a novel therapy for hemophilia B.

Arruda VR, Stedman HH, Haurigot V, Buchlis G, Baila S, Favaro P, Chen Y, Franck HG, Zhou S, Wright JF, Couto LB, Jiang H, Pierce GF, Bellinger DA, Mingozzi F, Nichols TC, High KA. Arruda VR, et al. Blood. 2010 Jun 10;115(23):4678-88. doi: 10.1182/blood-2009-12-261156. Epub 2010 Mar 24. Blood. 2010. PMID: 20335222 Free PMC article.

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