Saido TC - Search Results

1

Evidence that CD147 modulation of beta-amyloid (Abeta) levels is mediated by extracellular degradation of secreted Abeta.

Vetrivel KS, Zhang X, Meckler X, Cheng H, Lee S, Gong P, Lopes KO, Chen Y, Iwata N, Yin KJ, Lee JM, Parent AT, Saido TC, Li YM, Sisodia SS, Thinakaran G. Vetrivel KS, et al. Among authors: saido tc. J Biol Chem. 2008 Jul 11;283(28):19489-98. doi: 10.1074/jbc.M801037200. Epub 2008 May 1. J Biol Chem. 2008. PMID: 18456655 Free PMC article.

2

Neprilysin degrades both amyloid beta peptides 1-40 and 1-42 most rapidly and efficiently among thiorphan- and phosphoramidon-sensitive endopeptidases.

Shirotani K, Tsubuki S, Iwata N, Takaki Y, Harigaya W, Maruyama K, Kiryu-Seo S, Kiyama H, Iwata H, Tomita T, Iwatsubo T, Saido TC. Shirotani K, et al. Among authors: saido tc. J Biol Chem. 2001 Jun 15;276(24):21895-901. doi: 10.1074/jbc.M008511200. Epub 2001 Mar 6. J Biol Chem. 2001. PMID: 11278416 Free article.

3

Metabolic regulation of brain Abeta by neprilysin.

Iwata N, Tsubuki S, Takaki Y, Shirotani K, Lu B, Gerard NP, Gerard C, Hama E, Lee HJ, Saido TC. Iwata N, et al. Among authors: saido tc. Science. 2001 May 25;292(5521):1550-2. doi: 10.1126/science.1059946. Science. 2001. PMID: 11375493

4

Abeta-degrading endopeptidase, neprilysin, in mouse brain: synaptic and axonal localization inversely correlating with Abeta pathology.

Fukami S, Watanabe K, Iwata N, Haraoka J, Lu B, Gerard NP, Gerard C, Fraser P, Westaway D, St George-Hyslop P, Saido TC. Fukami S, et al. Among authors: saido tc. Neurosci Res. 2002 May;43(1):39-56. doi: 10.1016/s0168-0102(02)00015-9. Neurosci Res. 2002. PMID: 12074840

5

Region-specific reduction of A beta-degrading endopeptidase, neprilysin, in mouse hippocampus upon aging.

Iwata N, Takaki Y, Fukami S, Tsubuki S, Saido TC. Iwata N, et al. Among authors: saido tc. J Neurosci Res. 2002 Nov 1;70(3):493-500. doi: 10.1002/jnr.10390. J Neurosci Res. 2002. PMID: 12391610

6

Characterization of alpha 2,6-sialyltransferase cleavage by Alzheimer's beta -secretase (BACE1).

Kitazume S, Tachida Y, Oka R, Kotani N, Ogawa K, Suzuki M, Dohmae N, Takio K, Saido TC, Hashimoto Y. Kitazume S, et al. Among authors: saido tc. J Biol Chem. 2003 Apr 25;278(17):14865-71. doi: 10.1074/jbc.M206262200. Epub 2002 Dec 7. J Biol Chem. 2003. PMID: 12473667 Free article.

7

[Amyloid-beta peptide metabolism and Alzheimer's disease].

Iwata N, Saido TC. Iwata N, et al. Among authors: saido tc. Nihon Yakurigaku Zasshi. 2003 Jul;122(1):5-14. doi: 10.1254/fpj.122.5. Nihon Yakurigaku Zasshi. 2003. PMID: 12843567 Review. Japanese.

8

Alzheimer's disease, neuropeptides, neuropeptidase, and amyloid-beta peptide metabolism.

Saito T, Takaki Y, Iwata N, Trojanowski J, Saido TC. Saito T, et al. Among authors: saido tc. Sci Aging Knowledge Environ. 2003 Jan 22;2003(3):PE1. doi: 10.1126/sageke.2003.3.pe1. Sci Aging Knowledge Environ. 2003. PMID: 12844556 Review.

9

Oxidized neprilysin in aging and Alzheimer's disease brains.

Wang DS, Iwata N, Hama E, Saido TC, Dickson DW. Wang DS, et al. Among authors: saido tc. Biochem Biophys Res Commun. 2003 Oct 10;310(1):236-41. doi: 10.1016/j.bbrc.2003.09.003. Biochem Biophys Res Commun. 2003. PMID: 14511676

10

Presynaptic localization of neprilysin contributes to efficient clearance of amyloid-beta peptide in mouse brain.

Iwata N, Mizukami H, Shirotani K, Takaki Y, Muramatsu S, Lu B, Gerard NP, Gerard C, Ozawa K, Saido TC. Iwata N, et al. Among authors: saido tc. J Neurosci. 2004 Jan 28;24(4):991-8. doi: 10.1523/JNEUROSCI.4792-03.2004. J Neurosci. 2004. PMID: 14749444 Free PMC article.

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