Lee RE - Search Results

1

Pharmacokinetically-guided lead optimization of nitrofuranylamide anti-tuberculosis agents.

Budha NR, Mehrotra N, Tangallapally R, Rakesh, Qi J, Daniels AJ, Lee RE, Meibohm B. Budha NR, et al. Among authors: lee re. AAPS J. 2008;10(1):157-65. doi: 10.1208/s12248-008-9017-8. Epub 2008 Mar 14. AAPS J. 2008. PMID: 18446516 Free PMC article.

2

Crystal structure of 7,8-dihydropteroate synthase from Bacillus anthracis: mechanism and novel inhibitor design.

Babaoglu K, Qi J, Lee RE, White SW. Babaoglu K, et al. Among authors: lee re. Structure. 2004 Sep;12(9):1705-17. doi: 10.1016/j.str.2004.07.011. Structure. 2004. PMID: 15341734 Free article.

3

Synthesis and evaluation of nitrofuranylamides as novel antituberculosis agents.

Tangallapally RP, Yendapally R, Lee RE, Hevener K, Jones VC, Lenaerts AJ, McNeil MR, Wang Y, Franzblau S, Lee RE. Tangallapally RP, et al. Among authors: lee re. J Med Chem. 2004 Oct 7;47(21):5276-83. doi: 10.1021/jm049972y. J Med Chem. 2004. PMID: 15456272

4

Synthesis and evaluation of cyclic secondary amine substituted phenyl and benzyl nitrofuranyl amides as novel antituberculosis agents.

Tangallapally RP, Yendapally R, Lee RE, Lenaerts AJ, Lee RE. Tangallapally RP, et al. Among authors: lee re. J Med Chem. 2005 Dec 29;48(26):8261-9. doi: 10.1021/jm050765n. J Med Chem. 2005. PMID: 16366608 Free PMC article.

5

Synthesis of new and potent analogues of anti-tuberculosis agent 5-nitro-furan-2-carboxylic acid 4-(4-benzyl-piperazin-1-yl)-benzylamide with improved bioavailability.

Tangallapally RP, Lee RE, Lenaerts AJ, Lee RE. Tangallapally RP, et al. Among authors: lee re. Bioorg Med Chem Lett. 2006 May 15;16(10):2584-9. doi: 10.1016/j.bmcl.2006.02.048. Epub 2006 Mar 10. Bioorg Med Chem Lett. 2006. PMID: 16529927

6

Development of an etoposide prodrug for dual prodrug-enzyme antitumor therapy.

Yoon KJ, Qi J, Remack JS, Virga KG, Hatfield MJ, Potter PM, Lee RE, Danks MK. Yoon KJ, et al. Among authors: lee re. Mol Cancer Ther. 2006 Jun;5(6):1577-84. doi: 10.1158/1535-7163.MCT-06-0090. Mol Cancer Ther. 2006. PMID: 16818517

7

Acyl-phosphates initiate membrane phospholipid synthesis in Gram-positive pathogens.

Lu YJ, Zhang YM, Grimes KD, Qi J, Lee RE, Rock CO. Lu YJ, et al. Among authors: lee re. Mol Cell. 2006 Sep 1;23(5):765-72. doi: 10.1016/j.molcel.2006.06.030. Mol Cell. 2006. PMID: 16949372 Free article.

8

Nitrofurans as novel anti-tuberculosis agents: identification, development and evaluation.

Tangallapally RP, Yendapally R, Daniels AJ, Lee RE, Lee RE. Tangallapally RP, et al. Among authors: lee re. Curr Top Med Chem. 2007;7(5):509-26. doi: 10.2174/156802607780059772. Curr Top Med Chem. 2007. PMID: 17346196 Review.

9

Discovery of novel isoxazolines as anti-tuberculosis agents.

Tangallapally RP, Sun D, Rakesh, Budha N, Lee RE, Lenaerts AJ, Meibohm B, Lee RE. Tangallapally RP, et al. Among authors: lee re. Bioorg Med Chem Lett. 2007 Dec 1;17(23):6638-42. doi: 10.1016/j.bmcl.2007.09.048. Epub 2007 Sep 15. Bioorg Med Chem Lett. 2007. PMID: 17937983 Free PMC article.

10

Design, synthesis, and evaluation of novel ethambutol analogues.

Yendapally R, Lee RE. Yendapally R, et al. Among authors: lee re. Bioorg Med Chem Lett. 2008 Mar 1;18(5):1607-11. doi: 10.1016/j.bmcl.2008.01.065. Epub 2008 Jan 19. Bioorg Med Chem Lett. 2008. PMID: 18242089 Free PMC article.

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