Modeling and E-M estimation of haplotype-specific relative risks from genotype data for a case-control study of unrelated individuals.
Stram DO, Leigh Pearce C, Bretsky P, Freedman M, Hirschhorn JN, Altshuler D, Kolonel LN, Henderson BE, Thomas DC.
Stram DO, et al.
Hum Hered. 2003;55(4):179-90. doi: 10.1159/000073202.
Hum Hered. 2003.
PMID: 14566096
Our interest is to develop and evaluate extensions of methods, based on haplotype imputation, that have been recently described (Schaid et al., Am J Hum Genet, 2002, and Zaykin et al., Hum Hered, 2002) as providing score tests of the null hypothesis of no effect of SNP haplotypes …
Our interest is to develop and evaluate extensions of methods, based on haplotype imputation, that have been recently described (Schaid et a …