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Meta-analysis of vascular endothelial growth factor variations in amyotrophic lateral sclerosis: increased susceptibility in male carriers of the -2578AA genotype.
Lambrechts D, Poesen K, Fernández-Santiago R, Al-Chalabi A, Del Bo R, Van Vught PW, Khan S, Marklund SL, Brockington A, van Marion I, Anneser J, Shaw C, Ludolph AC, Leigh NP, Comi GP, Gasser T, Shaw PJ, Morrison KE, Andersen PM, Van den Berg LH, Thijs V, Siddique T, Robberecht W, Carmeliet P. Lambrechts D, et al. Among authors: carmeliet p. J Med Genet. 2009 Dec;46(12):840-6. doi: 10.1136/jmg.2008.058222. Epub 2008 Apr 15. J Med Genet. 2009. PMID: 18413368
Deletion of the hypoxia-response element in the vascular endothelial growth factor promoter causes motor neuron degeneration.
Oosthuyse B, Moons L, Storkebaum E, Beck H, Nuyens D, Brusselmans K, Van Dorpe J, Hellings P, Gorselink M, Heymans S, Theilmeier G, Dewerchin M, Laudenbach V, Vermylen P, Raat H, Acker T, Vleminckx V, Van Den Bosch L, Cashman N, Fujisawa H, Drost MR, Sciot R, Bruyninckx F, Hicklin DJ, Ince C, Gressens P, Lupu F, Plate KH, Robberecht W, Herbert JM, Collen D, Carmeliet P. Oosthuyse B, et al. Among authors: carmeliet p. Nat Genet. 2001 Jun;28(2):131-8. doi: 10.1038/88842. Nat Genet. 2001. PMID: 11381259
VEGF is a modifier of amyotrophic lateral sclerosis in mice and humans and protects motoneurons against ischemic death.
Lambrechts D, Storkebaum E, Morimoto M, Del-Favero J, Desmet F, Marklund SL, Wyns S, Thijs V, Andersson J, van Marion I, Al-Chalabi A, Bornes S, Musson R, Hansen V, Beckman L, Adolfsson R, Pall HS, Prats H, Vermeire S, Rutgeerts P, Katayama S, Awata T, Leigh N, Lang-Lazdunski L, Dewerchin M, Shaw C, Moons L, Vlietinck R, Morrison KE, Robberecht W, Van Broeckhoven C, Collen D, Andersen PM, Carmeliet P. Lambrechts D, et al. Among authors: carmeliet p. Nat Genet. 2003 Aug;34(4):383-94. doi: 10.1038/ng1211. Nat Genet. 2003. PMID: 12847526 Free article.
VEGF: a critical player in neurodegeneration.
Storkebaum E, Carmeliet P. Storkebaum E, et al. Among authors: carmeliet p. J Clin Invest. 2004 Jan;113(1):14-8. doi: 10.1172/JCI20682. J Clin Invest. 2004. PMID: 14702101 Free PMC article. Review.
Medicine: genetic spotlight on a blood defect.
Lambrechts D, Carmeliet P. Lambrechts D, et al. Among authors: carmeliet p. Nature. 2004 Feb 12;427(6975):592-4. doi: 10.1038/427592a. Nature. 2004. PMID: 14961101 No abstract available.
Sculpting heart valves with NFATc and VEGF.
Lambrechts D, Carmeliet P. Lambrechts D, et al. Among authors: carmeliet p. Cell. 2004 Sep 3;118(5):532-4. doi: 10.1016/j.cell.2004.08.022. Cell. 2004. PMID: 15339657 Free article. Review.
784 results