Sleegers K - Search Results

1

SORL1 is genetically associated with increased risk for late-onset Alzheimer disease in the Belgian population.

Bettens K, Brouwers N, Engelborghs S, De Deyn PP, Van Broeckhoven C, Sleegers K. Bettens K, et al. Among authors: sleegers k. Hum Mutat. 2008 May;29(5):769-70. doi: 10.1002/humu.20725. Hum Mutat. 2008. PMID: 18407551

2

The gene encoding nicastrin, a major gamma-secretase component, modifies risk for familial early-onset Alzheimer disease in a Dutch population-based sample.

Dermaut B, Theuns J, Sleegers K, Hasegawa H, Van den Broeck M, Vennekens K, Corsmit E, St George-Hyslop P, Cruts M, van Duijn CM, Van Broeckhoven C. Dermaut B, et al. Among authors: sleegers k. Am J Hum Genet. 2002 Jun;70(6):1568-74. doi: 10.1086/340732. Epub 2002 Apr 24. Am J Hum Genet. 2002. PMID: 11992262 Free PMC article.

3

Tau negative frontal lobe dementia at 17q21: significant finemapping of the candidate region to a 4.8 cM interval.

Rademakers R, Cruts M, Dermaut B, Sleegers K, Rosso SM, Van den Broeck M, Backhovens H, van Swieten J, van Duijn CM, Van Broeckhoven C. Rademakers R, et al. Among authors: sleegers k. Mol Psychiatry. 2002;7(10):1064-74. doi: 10.1038/sj.mp.4001198. Mol Psychiatry. 2002. PMID: 12476321

4

Familial clustering and genetic risk for dementia in a genetically isolated Dutch population.

Sleegers K, Roks G, Theuns J, Aulchenko YS, Rademakers R, Cruts M, van Gool WA, Van Broeckhoven C, Heutink P, Oostra BA, van Swieten JC, van Duijn CM. Sleegers K, et al. Brain. 2004 Jul;127(Pt 7):1641-9. doi: 10.1093/brain/awh179. Epub 2004 May 6. Brain. 2004. PMID: 15130954

5

Association of cyclin-dependent kinase 5 and neuronal activators p35 and p39 complex in early-onset Alzheimer's disease.

Rademakers R, Sleegers K, Theuns J, Van den Broeck M, Bel Kacem S, Nilsson LG, Adolfsson R, van Duijn CM, Van Broeckhoven C, Cruts M. Rademakers R, et al. Among authors: sleegers k. Neurobiol Aging. 2005 Aug-Sep;26(8):1145-51. doi: 10.1016/j.neurobiolaging.2004.10.003. Epub 2004 Dec 22. Neurobiol Aging. 2005. PMID: 15917097

6

Linkage and association studies identify a novel locus for Alzheimer disease at 7q36 in a Dutch population-based sample.

Rademakers R, Cruts M, Sleegers K, Dermaut B, Theuns J, Aulchenko Y, Weckx S, De Pooter T, Van den Broeck M, Corsmit E, De Rijk P, Del-Favero J, van Swieten J, van Duijn CM, Van Broeckhoven C. Rademakers R, et al. Among authors: sleegers k. Am J Hum Genet. 2005 Oct;77(4):643-52. doi: 10.1086/491749. Epub 2005 Aug 30. Am J Hum Genet. 2005. PMID: 16175510 Free PMC article.

7

High-density SNP haplotyping suggests altered regulation of tau gene expression in progressive supranuclear palsy.

Rademakers R, Melquist S, Cruts M, Theuns J, Del-Favero J, Poorkaj P, Baker M, Sleegers K, Crook R, De Pooter T, Bel Kacem S, Adamson J, Van den Bossche D, Van den Broeck M, Gass J, Corsmit E, De Rijk P, Thomas N, Engelborghs S, Heckman M, Litvan I, Crook J, De Deyn PP, Dickson D, Schellenberg GD, Van Broeckhoven C, Hutton ML. Rademakers R, et al. Among authors: sleegers k. Hum Mol Genet. 2005 Nov 1;14(21):3281-92. doi: 10.1093/hmg/ddi361. Epub 2005 Sep 29. Hum Mol Genet. 2005. PMID: 16195395

8

The UBQLN1 polymorphism, UBQ-8i, at 9q22 is not associated with Alzheimer's disease with onset before 70 years.

Brouwers N, Sleegers K, Engelborghs S, Bogaerts V, van Duijn CM, De Deyn PP, Van Broeckhoven C, Dermaut B. Brouwers N, et al. Among authors: sleegers k. Neurosci Lett. 2006 Jan 9;392(1-2):72-4. doi: 10.1016/j.neulet.2005.08.064. Epub 2005 Oct 6. Neurosci Lett. 2006. PMID: 16214290

9

Reduced hippocampal volume in non-demented carriers of the apolipoprotein E epsilon4: relation to chronological age and recognition memory.

Lind J, Larsson A, Persson J, Ingvar M, Nilsson LG, Bäckman L, Adolfsson R, Cruts M, Sleegers K, Van Broeckhoven C, Nyberg L. Lind J, et al. Among authors: sleegers k. Neurosci Lett. 2006 Mar 20;396(1):23-7. doi: 10.1016/j.neulet.2005.11.070. Epub 2006 Jan 6. Neurosci Lett. 2006. PMID: 16406347

10

Promoter mutations that increase amyloid precursor-protein expression are associated with Alzheimer disease.

Theuns J, Brouwers N, Engelborghs S, Sleegers K, Bogaerts V, Corsmit E, De Pooter T, van Duijn CM, De Deyn PP, Van Broeckhoven C. Theuns J, et al. Among authors: sleegers k. Am J Hum Genet. 2006 Jun;78(6):936-46. doi: 10.1086/504044. Epub 2006 Apr 10. Am J Hum Genet. 2006. PMID: 16685645 Free PMC article.

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