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The Cytomegalovirus M35 Protein Directly Binds to the Interferon-β Enhancer and Modulates Transcription of Ifnb1 and Other IRF3-Driven Genes.
Schwanke H, Gonçalves Magalhães V, Schmelz S, Wyler E, Hennig T, Günther T, Grundhoff A, Dölken L, Landthaler M, van Ham M, Jänsch L, Büssow K, van den Heuvel J, Blankenfeldt W, Friedel CC, Erhard F, Brinkmann MM. Schwanke H, et al. Among authors: blankenfeldt w. J Virol. 2023 Jun 29;97(6):e0040023. doi: 10.1128/jvi.00400-23. Epub 2023 Jun 8. J Virol. 2023. PMID: 37289084 Free PMC article.
Towards Translation of PqsR Inverse Agonists: From In Vitro Efficacy Optimization to In Vivo Proof-of-Principle.
Hamed MM, Abdelsamie AS, Rox K, Schütz C, Kany AM, Röhrig T, Schmelz S, Blankenfeldt W, Arce-Rodriguez A, Borrero-de Acuña JM, Jahn D, Rademacher J, Ringshausen FC, Cramer N, Tümmler B, Hirsch AKH, Hartmann RW, Empting M. Hamed MM, et al. Among authors: blankenfeldt w. Adv Sci (Weinh). 2023 Feb;10(5):e2204443. doi: 10.1002/advs.202204443. Epub 2023 Jan 3. Adv Sci (Weinh). 2023. PMID: 36596691 Free PMC article.
Moonlighting chaperone activity of the enzyme PqsE contributes to RhlR-controlled virulence of Pseudomonas aeruginosa.
Borgert SR, Henke S, Witzgall F, Schmelz S, Zur Lage S, Hotop SK, Stephen S, Lübken D, Krüger J, Gomez NO, van Ham M, Jänsch L, Kalesse M, Pich A, Brönstrup M, Häussler S, Blankenfeldt W. Borgert SR, et al. Among authors: blankenfeldt w. Nat Commun. 2022 Dec 1;13(1):7402. doi: 10.1038/s41467-022-35030-w. Nat Commun. 2022. PMID: 36456567 Free PMC article.
Analysis of the eukaryotic prenylome by isoprenoid affinity tagging.
Nguyen UT, Guo Z, Delon C, Wu Y, Deraeve C, Fränzel B, Bon RS, Blankenfeldt W, Goody RS, Waldmann H, Wolters D, Alexandrov K. Nguyen UT, et al. Among authors: blankenfeldt w. Nat Chem Biol. 2009 Apr;5(4):227-35. doi: 10.1038/nchembio.149. Epub 2009 Feb 15. Nat Chem Biol. 2009. PMID: 19219049
130 results