Alexandrov K - Search Results

1

Development of selective RabGGTase inhibitors and crystal structure of a RabGGTase-inhibitor complex.

Guo Z, Wu YW, Tan KT, Bon RS, Guiu-Rozas E, Delon C, Nguyen TU, Wetzel S, Arndt S, Goody RS, Blankenfeldt W, Alexandrov K, Waldmann H. Guo Z, et al. Among authors: alexandrov k. Angew Chem Int Ed Engl. 2008;47(20):3747-50. doi: 10.1002/anie.200705795. Angew Chem Int Ed Engl. 2008. PMID: 18399557 No abstract available.

2

Moderate discrimination of REP-1 between Rab7 x GDP and Rab7 x GTP arises from a difference of an order of magnitude in dissociation rates.

Alexandrov K, Simon I, Iakovenko A, Holz B, Goody RS, Scheidig AJ. Alexandrov K, et al. FEBS Lett. 1998 Apr 3;425(3):460-4. doi: 10.1016/s0014-5793(98)00290-7. FEBS Lett. 1998. PMID: 9563513 Free article.

3

Characterization of the ternary complex between Rab7, REP-1 and Rab geranylgeranyl transferase.

Alexandrov K, Simon I, Yurchenko V, Iakovenko A, Rostkova E, Scheidig AJ, Goody RS. Alexandrov K, et al. Eur J Biochem. 1999 Oct 1;265(1):160-70. doi: 10.1046/j.1432-1327.1999.00699.x. Eur J Biochem. 1999. PMID: 10491170 Free article.

4

Semi-synthetic Rab proteins as tools for studying intermolecular interactions.

Iakovenko A, Rostkova E, Merzlyak E, Hillebrand AM, Thomä NH, Goody RS, Alexandrov K. Iakovenko A, et al. Among authors: alexandrov k. FEBS Lett. 2000 Feb 25;468(2-3):155-8. doi: 10.1016/s0014-5793(00)01143-1. FEBS Lett. 2000. PMID: 10692577 Free article.

5

High-resolution crystal structure of S. cerevisiae Ypt51(DeltaC15)-GppNHp, a small GTP-binding protein involved in regulation of endocytosis.

Esters H, Alexandrov K, Constantinescu AT, Goody RS, Scheidig AJ. Esters H, et al. Among authors: alexandrov k. J Mol Biol. 2000 Apr 21;298(1):111-21. doi: 10.1006/jmbi.2000.3645. J Mol Biol. 2000. PMID: 10756108

6

Phosphoisoprenoid binding specificity of geranylgeranyltransferase type II.

Thomä NH, Iakovenko A, Owen D, Scheidig AS, Waldmann H, Goody RS, Alexandrov K. Thomä NH, et al. Among authors: alexandrov k. Biochemistry. 2000 Oct 3;39(39):12043-52. doi: 10.1021/bi000835m. Biochemistry. 2000. PMID: 11009619

7

Crystal structure of the GAP domain of Gyp1p: first insights into interaction with Ypt/Rab proteins.

Rak A, Fedorov R, Alexandrov K, Albert S, Goody RS, Gallwitz D, Scheidig AJ. Rak A, et al. Among authors: alexandrov k. EMBO J. 2000 Oct 2;19(19):5105-13. doi: 10.1093/emboj/19.19.5105. EMBO J. 2000. PMID: 11013213 Free PMC article.

8

Allosteric regulation of substrate binding and product release in geranylgeranyltransferase type II.

Thomä NH, Iakovenko A, Kalinin A, Waldmann H, Goody RS, Alexandrov K. Thomä NH, et al. Among authors: alexandrov k. Biochemistry. 2001 Jan 9;40(1):268-74. doi: 10.1021/bi002034p. Biochemistry. 2001. PMID: 11141079

9

Fluorescence methods for monitoring interactions of Rab proteins with nucleotides, Rab escort protein, and geranylgeranyltransferase.

Alexandrov K, Scheidig AJ, Goody RS. Alexandrov K, et al. Methods Enzymol. 2001;329:14-31. doi: 10.1016/s0076-6879(01)29062-4. Methods Enzymol. 2001. PMID: 11210530 No abstract available.

10

Vps9, Rabex-5 and DSS4: proteins with weak but distinct nucleotide-exchange activities for Rab proteins.

Esters H, Alexandrov K, Iakovenko A, Ivanova T, Thomä N, Rybin V, Zerial M, Scheidig AJ, Goody RS. Esters H, et al. Among authors: alexandrov k. J Mol Biol. 2001 Jun 29;310(1):141-56. doi: 10.1006/jmbi.2001.4735. J Mol Biol. 2001. PMID: 11419942

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