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Page 1
Using dimensional models of externalizing psychopathology to aid in gene identification.
Dick DM, Aliev F, Wang JC, Grucza RA, Schuckit M, Kuperman S, Kramer J, Hinrichs A, Bertelsen S, Budde JP, Hesselbrock V, Porjesz B, Edenberg HJ, Bierut LJ, Goate A. Dick DM, et al. Among authors: budde jp. Arch Gen Psychiatry. 2008 Mar;65(3):310-8. doi: 10.1001/archpsyc.65.3.310. Arch Gen Psychiatry. 2008. PMID: 18316677
Cell-free RNA signatures predict Alzheimer's disease.
Cisterna-García A, Beric A, Ali M, Pardo JA, Chen HH, Fernandez MV, Norton J, Gentsch J, Bergmann K, Budde J, Perlmutter JS, Morris JC, Cruchaga C, Botia JA, Ibanez L. Cisterna-García A, et al. iScience. 2023 Nov 23;26(12):108534. doi: 10.1016/j.isci.2023.108534. eCollection 2023 Dec 15. iScience. 2023. PMID: 38089583 Free PMC article.
Novel early-onset Alzheimer-associated genes influence risk through dysregulation of glutamate, immune activation, and intracell signaling pathways.
Cruchaga C, Bradley J, Western D, Wang C, Lucio Da Fonseca E, Neupane A, Kurup J, Ray N, Jean-Francois M, Gorijala P, Bergmann K, Budde J, Martin E, Pericak-Vance M, Cuccaro M, Kunkle B, Morris J, Holtzman D, Perrin R, Naj A, Haines J, Schellenberg G, Fernandez V, Reitz C, Beecham G; Alzheimer’s Disease Genetics Consortium; Charles F. and Joanne Knight Alzheimer’s disease research center Knight ADRC. Cruchaga C, et al. Res Sq [Preprint]. 2024 Jun 5:rs.3.rs-4480585. doi: 10.21203/rs.3.rs-4480585/v1. Res Sq. 2024. PMID: 38883718 Free PMC article. Preprint.
Multi-cohort cerebrospinal fluid proteomics identifies robust molecular signatures for asymptomatic and symptomatic Alzheimer's disease.
Cruchaga C, Ali M, Shen Y, Do A, Wang L, Western D, Liu M, Beric A, Budde J, Gentsch J, Schindler S, Morris J, Holtzman D, Fernández M, Ruiz A, Alvarez I, Aguilar M, Pastor P, Rutledge J, Oh H, Wilson E, Le Guen Y, Khalid R, Robins C, Pulford D, Ibanez L, Wyss-Coray T, Ju Sung Y. Cruchaga C, et al. Res Sq [Preprint]. 2024 Feb 16:rs.3.rs-3631708. doi: 10.21203/rs.3.rs-3631708/v1. Res Sq. 2024. PMID: 38410465 Free PMC article. Preprint.
Organ aging signatures in the plasma proteome track health and disease.
Oh HS, Rutledge J, Nachun D, Pálovics R, Abiose O, Moran-Losada P, Channappa D, Urey DY, Kim K, Sung YJ, Wang L, Timsina J, Western D, Liu M, Kohlfeld P, Budde J, Wilson EN, Guen Y, Maurer TM, Haney M, Yang AC, He Z, Greicius MD, Andreasson KI, Sathyan S, Weiss EF, Milman S, Barzilai N, Cruchaga C, Wagner AD, Mormino E, Lehallier B, Henderson VW, Longo FM, Montgomery SB, Wyss-Coray T. Oh HS, et al. Nature. 2023 Dec;624(7990):164-172. doi: 10.1038/s41586-023-06802-1. Epub 2023 Dec 6. Nature. 2023. PMID: 38057571 Free PMC article.
Evidence of common and specific genetic effects: association of the muscarinic acetylcholine receptor M2 (CHRM2) gene with alcohol dependence and major depressive syndrome.
Wang JC, Hinrichs AL, Stock H, Budde J, Allen R, Bertelsen S, Kwon JM, Wu W, Dick DM, Rice J, Jones K, Nurnberger JI Jr, Tischfield J, Porjesz B, Edenberg HJ, Hesselbrock V, Crowe R, Schuckit M, Begleiter H, Reich T, Goate AM, Bierut LJ. Wang JC, et al. Hum Mol Genet. 2004 Sep 1;13(17):1903-11. doi: 10.1093/hmg/ddh194. Epub 2004 Jun 30. Hum Mol Genet. 2004. PMID: 15229186
Functional variant in a bitter-taste receptor (hTAS2R16) influences risk of alcohol dependence.
Hinrichs AL, Wang JC, Bufe B, Kwon JM, Budde J, Allen R, Bertelsen S, Evans W, Dick D, Rice J, Foroud T, Nurnberger J, Tischfield JA, Kuperman S, Crowe R, Hesselbrock V, Schuckit M, Almasy L, Porjesz B, Edenberg HJ, Begleiter H, Meyerhof W, Bierut LJ, Goate AM. Hinrichs AL, et al. Am J Hum Genet. 2006 Jan;78(1):103-11. doi: 10.1086/499253. Epub 2005 Nov 21. Am J Hum Genet. 2006. PMID: 16385453 Free PMC article.
HDDD2 is a familial frontotemporal lobar degeneration with ubiquitin-positive, tau-negative inclusions caused by a missense mutation in the signal peptide of progranulin.
Mukherjee O, Pastor P, Cairns NJ, Chakraverty S, Kauwe JS, Shears S, Behrens MI, Budde J, Hinrichs AL, Norton J, Levitch D, Taylor-Reinwald L, Gitcho M, Tu PH, Tenenholz Grinberg L, Liscic RM, Armendariz J, Morris JC, Goate AM. Mukherjee O, et al. Ann Neurol. 2006 Sep;60(3):314-22. doi: 10.1002/ana.20963. Ann Neurol. 2006. PMID: 16983685 Free PMC article.
Functional variants in TAS2R38 and TAS2R16 influence alcohol consumption in high-risk families of African-American origin.
Wang JC, Hinrichs AL, Bertelsen S, Stock H, Budde JP, Dick DM, Bucholz KK, Rice J, Saccone N, Edenberg HJ, Hesselbrock V, Kuperman S, Schuckit MA, Bierut LJ, Goate AM. Wang JC, et al. Among authors: budde jp. Alcohol Clin Exp Res. 2007 Feb;31(2):209-15. doi: 10.1111/j.1530-0277.2006.00297.x. Alcohol Clin Exp Res. 2007. PMID: 17250611
Family-based association analyses of alcohol dependence phenotypes across DRD2 and neighboring gene ANKK1.
Dick DM, Wang JC, Plunkett J, Aliev F, Hinrichs A, Bertelsen S, Budde JP, Goldstein EL, Kaplan D, Edenberg HJ, Nurnberger J Jr, Hesselbrock V, Schuckit M, Kuperman S, Tischfield J, Porjesz B, Begleiter H, Bierut LJ, Goate A. Dick DM, et al. Among authors: budde jp. Alcohol Clin Exp Res. 2007 Oct;31(10):1645-53. doi: 10.1111/j.1530-0277.2007.00470.x. Alcohol Clin Exp Res. 2007. PMID: 17850642
80 results