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Failure to confirm allelic association between markers at the CAPON gene locus and schizophrenia in a British sample.
Puri V, McQuillin A, Thirumalai S, Lawrence J, Krasucki R, Choudhury K, Datta S, Kerwin S, Quested D, Bass N, Pimm J, Lamb G, Moorey H, Kandasami G, Badacsonyi A, Kelly K, Morgan J, Punukollu B, Nadeem H, Curtis D, Gurling HM. Puri V, et al. Among authors: gurling hm. Biol Psychiatry. 2006 Jan 15;59(2):195-7. doi: 10.1016/j.biopsych.2005.08.015. Epub 2005 Oct 3. Biol Psychiatry. 2006. PMID: 16202394 Clinical Trial.
Genetic association and brain morphology studies and the chromosome 8p22 pericentriolar material 1 (PCM1) gene in susceptibility to schizophrenia.
Gurling HM, Critchley H, Datta SR, McQuillin A, Blaveri E, Thirumalai S, Pimm J, Krasucki R, Kalsi G, Quested D, Lawrence J, Bass N, Choudhury K, Puri V, O'Daly O, Curtis D, Blackwood D, Muir W, Malhotra AK, Buchanan RW, Good CD, Frackowiak RS, Dolan RJ. Gurling HM, et al. Arch Gen Psychiatry. 2006 Aug;63(8):844-54. doi: 10.1001/archpsyc.63.8.844. Arch Gen Psychiatry. 2006. PMID: 16894060 Free PMC article.
A genetic association study of chromosome 11q22-24 in two different samples implicates the FXYD6 gene, encoding phosphohippolin, in susceptibility to schizophrenia.
Choudhury K, McQuillin A, Puri V, Pimm J, Datta S, Thirumalai S, Krasucki R, Lawrence J, Bass NJ, Quested D, Crombie C, Fraser G, Walker N, Nadeem H, Johnson S, Curtis D, St Clair D, Gurling HM. Choudhury K, et al. Among authors: gurling hm. Am J Hum Genet. 2007 Apr;80(4):664-72. doi: 10.1086/513475. Epub 2007 Mar 1. Am J Hum Genet. 2007. PMID: 17357072 Free PMC article.
No evidence for excess runs of homozygosity in bipolar disorder.
Vine AE, McQuillin A, Bass NJ, Pereira A, Kandaswamy R, Robinson M, Lawrence J, Anjorin A, Sklar P, Gurling HM, Curtis D. Vine AE, et al. Among authors: gurling hm. Psychiatr Genet. 2009 Aug;19(4):165-70. doi: 10.1097/YPG.0b013e32832a4faa. Psychiatr Genet. 2009. PMID: 19451863
Case-case genome-wide association analysis shows markers differentially associated with schizophrenia and bipolar disorder and implicates calcium channel genes.
Curtis D, Vine AE, McQuillin A, Bass NJ, Pereira A, Kandaswamy R, Lawrence J, Anjorin A, Choudhury K, Datta SR, Puri V, Krasucki R, Pimm J, Thirumalai S, Quested D, Gurling HM. Curtis D, et al. Among authors: gurling hm. Psychiatr Genet. 2011 Feb;21(1):1-4. doi: 10.1097/YPG.0b013e3283413382. Psychiatr Genet. 2011. PMID: 21057379 Free PMC article.
A threonine to isoleucine missense mutation in the pericentriolar material 1 gene is strongly associated with schizophrenia.
Datta SR, McQuillin A, Rizig M, Blaveri E, Thirumalai S, Kalsi G, Lawrence J, Bass NJ, Puri V, Choudhury K, Pimm J, Crombie C, Fraser G, Walker N, Curtis D, Zvelebil M, Pereira A, Kandaswamy R, St Clair D, Gurling HM. Datta SR, et al. Among authors: gurling hm. Mol Psychiatry. 2010 Jun;15(6):615-28. doi: 10.1038/mp.2008.128. Epub 2008 Dec 2. Mol Psychiatry. 2010. PMID: 19048012
116 results