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Antitumor activity mediated by CpG: the route of administration is critical.
Lou Y, Liu C, Lizée G, Peng W, Xu C, Ye Y, Rabinovich BA, Hailemichael Y, Gelbard A, Zhou D, Overwijk WW, Hwu P. Lou Y, et al. Among authors: liu c. J Immunother. 2011 Apr;34(3):279-88. doi: 10.1097/CJI.0b013e31820d2a05. J Immunother. 2011. PMID: 21389870 Free PMC article.
Persistent antigen at vaccination sites induces tumor-specific CD8⁺ T cell sequestration, dysfunction and deletion.
Hailemichael Y, Dai Z, Jaffarzad N, Ye Y, Medina MA, Huang XF, Dorta-Estremera SM, Greeley NR, Nitti G, Peng W, Liu C, Lou Y, Wang Z, Ma W, Rabinovich B, Sowell RT, Schluns KS, Davis RE, Hwu P, Overwijk WW. Hailemichael Y, et al. Among authors: liu c. Nat Med. 2013 Apr;19(4):465-72. doi: 10.1038/nm.3105. Epub 2013 Mar 3. Nat Med. 2013. PMID: 23455713 Free PMC article.
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