Geerts D - Search Results

1

The MSX1 homeobox transcription factor is a downstream target of PHOX2B and activates the Delta-Notch pathway in neuroblastoma.

Revet I, Huizenga G, Chan A, Koster J, Volckmann R, van Sluis P, Øra I, Versteeg R, Geerts D. Revet I, et al. Among authors: geerts d. Exp Cell Res. 2008 Feb 15;314(4):707-19. doi: 10.1016/j.yexcr.2007.12.008. Epub 2008 Jan 16. Exp Cell Res. 2008. PMID: 18201699

2

MSX1 induces the Wnt pathway antagonist genes DKK1, DKK2, DKK3, and SFRP1 in neuroblastoma cells, but does not block Wnt3 and Wnt5A signalling to DVL3.

Revet I, Huizenga G, Koster J, Volckmann R, van Sluis P, Versteeg R, Geerts D. Revet I, et al. Among authors: geerts d. Cancer Lett. 2010 Mar 28;289(2):195-207. doi: 10.1016/j.canlet.2009.08.019. Epub 2009 Oct 7. Cancer Lett. 2010. PMID: 19815336

3

MEIS homeobox genes in neuroblastoma.

Geerts D, Revet I, Jorritsma G, Schilderink N, Versteeg R. Geerts D, et al. Cancer Lett. 2005 Oct 18;228(1-2):43-50. doi: 10.1016/j.canlet.2005.01.047. Cancer Lett. 2005. PMID: 15919149 Review.

4

Cyclin D1 is a direct transcriptional target of GATA3 in neuroblastoma tumor cells.

Molenaar JJ, Ebus ME, Koster J, Santo E, Geerts D, Versteeg R, Caron HN. Molenaar JJ, et al. Among authors: geerts d. Oncogene. 2010 May 6;29(18):2739-45. doi: 10.1038/onc.2010.21. Epub 2010 Feb 15. Oncogene. 2010. PMID: 20154722

5

The polyamine metabolism genes ornithine decarboxylase and antizyme 2 predict aggressive behavior in neuroblastomas with and without MYCN amplification.

Geerts D, Koster J, Albert D, Koomoa DL, Feith DJ, Pegg AE, Volckmann R, Caron H, Versteeg R, Bachmann AS. Geerts D, et al. Int J Cancer. 2010 May 1;126(9):2012-24. doi: 10.1002/ijc.25074. Int J Cancer. 2010. PMID: 19960435 Free PMC article.

6

The role of the MEIS homeobox genes in neuroblastoma.

Geerts D, Schilderink N, Jorritsma G, Versteeg R. Geerts D, et al. Cancer Lett. 2003 Jul 18;197(1-2):87-92. doi: 10.1016/s0304-3835(03)00087-9. Cancer Lett. 2003. PMID: 12880965 Review.

7

Domain-wide regulation of gene expression in the human genome.

Gierman HJ, Indemans MH, Koster J, Goetze S, Seppen J, Geerts D, van Driel R, Versteeg R. Gierman HJ, et al. Among authors: geerts d. Genome Res. 2007 Sep;17(9):1286-95. doi: 10.1101/gr.6276007. Epub 2007 Aug 10. Genome Res. 2007. PMID: 17693573 Free PMC article.

8

Inactivation of CDK2 is synthetically lethal to MYCN over-expressing cancer cells.

Molenaar JJ, Ebus ME, Geerts D, Koster J, Lamers F, Valentijn LJ, Westerhout EM, Versteeg R, Caron HN. Molenaar JJ, et al. Among authors: geerts d. Proc Natl Acad Sci U S A. 2009 Aug 4;106(31):12968-73. doi: 10.1073/pnas.0901418106. Epub 2009 Jun 12. Proc Natl Acad Sci U S A. 2009. PMID: 19525400 Free PMC article.

9

Silencing of SPRY1 triggers complete regression of rhabdomyosarcoma tumors carrying a mutated RAS gene.

Schaaf G, Hamdi M, Zwijnenburg D, Lakeman A, Geerts D, Versteeg R, Kool M. Schaaf G, et al. Among authors: geerts d. Cancer Res. 2010 Jan 15;70(2):762-71. doi: 10.1158/0008-5472.CAN-09-2532. Epub 2010 Jan 12. Cancer Res. 2010. PMID: 20068162

10

Effect of sulfasalazine on human neuroblastoma: analysis of sepiapterin reductase (SPR) as a new therapeutic target.

Yco LP, Geerts D, Mocz G, Koster J, Bachmann AS. Yco LP, et al. Among authors: geerts d. BMC Cancer. 2015 Jun 21;15:477. doi: 10.1186/s12885-015-1447-y. BMC Cancer. 2015. PMID: 26093909 Free PMC article.

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