Bornmann WG - Search Results

1

Sorafenib induces apoptosis of AML cells via Bim-mediated activation of the intrinsic apoptotic pathway.

Zhang W, Konopleva M, Ruvolo VR, McQueen T, Evans RL, Bornmann WG, McCubrey J, Cortes J, Andreeff M. Zhang W, et al. Among authors: bornmann wg. Leukemia. 2008 Apr;22(4):808-18. doi: 10.1038/sj.leu.2405098. Epub 2008 Jan 17. Leukemia. 2008. PMID: 18200035

2

Concomitant inhibition of MDM2 and Bcl-2 protein function synergistically induce mitochondrial apoptosis in AML.

Kojima K, Konopleva M, Samudio IJ, Schober WD, Bornmann WG, Andreeff M. Kojima K, et al. Among authors: bornmann wg. Cell Cycle. 2006 Dec;5(23):2778-86. doi: 10.4161/cc.5.23.3520. Epub 2006 Dec 1. Cell Cycle. 2006. PMID: 17172851

3

Evaluation of apoptosis induction by concomitant inhibition of MEK, mTOR, and Bcl-2 in human acute myelogenous leukemia cells.

Zhang W, Ruvolo VR, Gao C, Zhou L, Bornmann W, Tsao T, Schober WD, Smith P, Guichard S, Konopleva M, Andreeff M. Zhang W, et al. Mol Cancer Ther. 2014 Jul;13(7):1848-59. doi: 10.1158/1535-7163.MCT-13-0576. Epub 2014 Apr 16. Mol Cancer Ther. 2014. PMID: 24739393 Free PMC article.

4

MEK inhibition enhances ABT-737-induced leukemia cell apoptosis via prevention of ERK-activated MCL-1 induction and modulation of MCL-1/BIM complex.

Konopleva M, Milella M, Ruvolo P, Watts JC, Ricciardi MR, Korchin B, McQueen T, Bornmann W, Tsao T, Bergamo P, Mak DH, Chen W, McCubrey J, Tafuri A, Andreeff M. Konopleva M, et al. Leukemia. 2012 Apr;26(4):778-87. doi: 10.1038/leu.2011.287. Epub 2011 Nov 8. Leukemia. 2012. Retraction in: Leukemia. 2024 Sep;38(9):2072. doi: 10.1038/s41375-024-02339-y PMID: 22064351 Free PMC article. Retracted.

5

Pharmacologic inhibition of fatty acid oxidation sensitizes human leukemia cells to apoptosis induction.

Samudio I, Harmancey R, Fiegl M, Kantarjian H, Konopleva M, Korchin B, Kaluarachchi K, Bornmann W, Duvvuri S, Taegtmeyer H, Andreeff M. Samudio I, et al. J Clin Invest. 2010 Jan;120(1):142-56. doi: 10.1172/JCI38942. Epub 2009 Dec 21. J Clin Invest. 2010. PMID: 20038799 Free PMC article.

6

Biguanides sensitize leukemia cells to ABT-737-induced apoptosis by inhibiting mitochondrial electron transport.

Velez J, Pan R, Lee JT, Enciso L, Suarez M, Duque JE, Jaramillo D, Lopez C, Morales L, Bornmann W, Konopleva M, Krystal G, Andreeff M, Samudio I. Velez J, et al. Oncotarget. 2016 Aug 9;7(32):51435-51449. doi: 10.18632/oncotarget.9843. Oncotarget. 2016. PMID: 27283492 Free PMC article.

7

A novel mechanism of action of methyl-2-cyano-3,12 dioxoolean-1,9 diene-28-oate: direct permeabilization of the inner mitochondrial membrane to inhibit electron transport and induce apoptosis.

Samudio I, Konopleva M, Pelicano H, Huang P, Frolova O, Bornmann W, Ying Y, Evans R, Contractor R, Andreeff M. Samudio I, et al. Mol Pharmacol. 2006 Apr;69(4):1182-93. doi: 10.1124/mol.105.018051. Epub 2006 Jan 12. Mol Pharmacol. 2006. PMID: 16410408

8

Mechanisms of antileukemic activity of the novel Bcl-2 homology domain-3 mimetic GX15-070 (obatoclax).

Konopleva M, Watt J, Contractor R, Tsao T, Harris D, Estrov Z, Bornmann W, Kantarjian H, Viallet J, Samudio I, Andreeff M. Konopleva M, et al. Cancer Res. 2008 May 1;68(9):3413-20. doi: 10.1158/0008-5472.CAN-07-1919. Cancer Res. 2008. PMID: 18451169 Free PMC article.

9

Adenovirus 5 E1A enhances histone deacetylase inhibitors-induced apoptosis through Egr-1-mediated Bim upregulation.

Yamaguchi H, Chen CT, Chou CK, Pal A, Bornmann W, Hortobagyi GN, Hung MC. Yamaguchi H, et al. Oncogene. 2010 Oct 14;29(41):5619-29. doi: 10.1038/onc.2010.295. Epub 2010 Aug 2. Oncogene. 2010. PMID: 20676141 Free PMC article.

10

Kit inhibitor APcK110 induces apoptosis and inhibits proliferation of acute myeloid leukemia cells.

Faderl S, Pal A, Bornmann W, Albitar M, Maxwell D, Van Q, Peng Z, Harris D, Liu Z, Hazan-Halevy I, Kantarjian HM, Estrov Z. Faderl S, et al. Cancer Res. 2009 May 1;69(9):3910-7. doi: 10.1158/0008-5472.CAN-08-0034. Epub 2009 Apr 21. Cancer Res. 2009. PMID: 19383925 Free PMC article.

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