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The VIZIER project: preparedness against pathogenic RNA viruses.
Coutard B, Gorbalenya AE, Snijder EJ, Leontovich AM, Poupon A, De Lamballerie X, Charrel R, Gould EA, Gunther S, Norder H, Klempa B, Bourhy H, Rohayem J, L'hermite E, Nordlund P, Stuart DI, Owens RJ, Grimes JM, Tucker PA, Bolognesi M, Mattevi A, Coll M, Jones TA, Aqvist J, Unge T, Hilgenfeld R, Bricogne G, Neyts J, La Colla P, Puerstinger G, Gonzalez JP, Leroy E, Cambillau C, Romette JL, Canard B. Coutard B, et al. Among authors: neyts j. Antiviral Res. 2008 Apr;78(1):37-46. doi: 10.1016/j.antiviral.2007.10.013. Epub 2007 Nov 29. Antiviral Res. 2008. PMID: 18083241 Free PMC article.
Improved crystallization of the coxsackievirus B3 RNA-dependent RNA polymerase.
Jabafi I, Selisko B, Coutard B, De Palma AM, Neyts J, Egloff MP, Grisel S, Dalle K, Campanacci V, Spinelli S, Cambillau C, Canard B, Gruez A. Jabafi I, et al. Among authors: neyts j. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2007 Jun 1;63(Pt 6):495-8. doi: 10.1107/S1744309107020416. Epub 2007 May 12. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2007. PMID: 17554171 Free PMC article.
Molecular strategies to inhibit the replication of RNA viruses.
Leyssen P, De Clercq E, Neyts J. Leyssen P, et al. Among authors: neyts j. Antiviral Res. 2008 Apr;78(1):9-25. doi: 10.1016/j.antiviral.2008.01.004. Epub 2008 Feb 4. Antiviral Res. 2008. PMID: 18313769 Free PMC article. Review.
The thiazolobenzimidazole TBZE-029 inhibits enterovirus replication by targeting a short region immediately downstream from motif C in the nonstructural protein 2C.
De Palma AM, Heggermont W, Lanke K, Coutard B, Bergmann M, Monforte AM, Canard B, De Clercq E, Chimirri A, Pürstinger G, Rohayem J, van Kuppeveld F, Neyts J. De Palma AM, et al. Among authors: neyts j. J Virol. 2008 May;82(10):4720-30. doi: 10.1128/JVI.01338-07. Epub 2008 Mar 12. J Virol. 2008. PMID: 18337578 Free PMC article.
The crystal structure of coxsackievirus B3 RNA-dependent RNA polymerase in complex with its protein primer VPg confirms the existence of a second VPg binding site on Picornaviridae polymerases.
Gruez A, Selisko B, Roberts M, Bricogne G, Bussetta C, Jabafi I, Coutard B, De Palma AM, Neyts J, Canard B. Gruez A, et al. Among authors: neyts j. J Virol. 2008 Oct;82(19):9577-90. doi: 10.1128/JVI.00631-08. Epub 2008 Jul 16. J Virol. 2008. PMID: 18632861 Free PMC article.
675 results