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Antiinflammatory glucocorticoid receptor ligand with reduced side effects exhibits an altered protein-protein interaction profile.
Miner JN, Ardecky B, Benbatoul K, Griffiths K, Larson CJ, Mais DE, Marschke K, Rosen J, Vajda E, Zhi L, Negro-Vilar A. Miner JN, et al. Among authors: vajda e. Proc Natl Acad Sci U S A. 2007 Dec 4;104(49):19244-9. doi: 10.1073/pnas.0705517104. Epub 2007 Nov 21. Proc Natl Acad Sci U S A. 2007. PMID: 18032610 Free PMC article.
Pharmacokinetics and pharmacodynamics of single and multiple doses of the glucagon receptor antagonist LGD-6972 in healthy subjects and subjects with type 2 diabetes mellitus.
Vajda EG, Logan D, Lasseter K, Armas D, Plotkin DJ, Pipkin JD, Li YX, Zhou R, Klein D, Wei X, Dilzer S, Zhi L, Marschke KB. Vajda EG, et al. Diabetes Obes Metab. 2017 Jan;19(1):24-32. doi: 10.1111/dom.12752. Epub 2016 Aug 31. Diabetes Obes Metab. 2017. PMID: 27501510 Free PMC article.
Pharmacokinetics and pharmacodynamics of LGD-3303 [9-chloro-2-ethyl-1-methyl-3-(2,2,2-trifluoroethyl)-3H-pyrrolo-[3,2-f]quinolin-7(6H)-one], an orally available nonsteroidal-selective androgen receptor modulator.
Vajda EG, López FJ, Rix P, Hill R, Chen Y, Lee KJ, O'Brien Z, Chang WY, Meglasson MD, Lee YH. Vajda EG, et al. J Pharmacol Exp Ther. 2009 Feb;328(2):663-70. doi: 10.1124/jpet.108.146811. Epub 2008 Nov 18. J Pharmacol Exp Ther. 2009. PMID: 19017848
45 results