Perlman ME - Search Results

1

Development of a self-emulsifying formulation that reduces the food effect for torcetrapib.

Perlman ME, Murdande SB, Gumkowski MJ, Shah TS, Rodricks CM, Thornton-Manning J, Freel D, Erhart LC. Perlman ME, et al. Int J Pharm. 2008 Mar 3;351(1-2):15-22. doi: 10.1016/j.ijpharm.2007.09.015. Epub 2007 Sep 19. Int J Pharm. 2008. PMID: 18024021

2

In vitro-in vivo evaluation of lipid based formulations of the CETP inhibitors CP-529,414 (torcetrapib) and CP-532,623.

McEvoy CL, Trevaskis NL, Edwards GA, Perlman ME, Ambler CM, Mack MC, Brockhurst B, Porter CJ. McEvoy CL, et al. Among authors: perlman me. Eur J Pharm Biopharm. 2014 Nov;88(3):973-85. doi: 10.1016/j.ejpb.2014.08.006. Epub 2014 Aug 23. Eur J Pharm Biopharm. 2014. PMID: 25152213

3

Correlating in Vitro Solubilization and Supersaturation Profiles with in Vivo Exposure for Lipid Based Formulations of the CETP Inhibitor CP-532,623.

McEvoy CL, Trevaskis NL, Feeney OM, Edwards GA, Perlman ME, Ambler CM, Porter CJH. McEvoy CL, et al. Among authors: perlman me. Mol Pharm. 2017 Dec 4;14(12):4525-4538. doi: 10.1021/acs.molpharmaceut.7b00660. Epub 2017 Nov 9. Mol Pharm. 2017. PMID: 29076741

4

Raising high-density lipoprotein in humans through inhibition of cholesteryl ester transfer protein: an initial multidose study of torcetrapib.

Clark RW, Sutfin TA, Ruggeri RB, Willauer AT, Sugarman ED, Magnus-Aryitey G, Cosgrove PG, Sand TM, Wester RT, Williams JA, Perlman ME, Bamberger MJ. Clark RW, et al. Among authors: perlman me. Arterioscler Thromb Vasc Biol. 2004 Mar;24(3):490-7. doi: 10.1161/01.ATV.0000118278.21719.17. Epub 2004 Jan 22. Arterioscler Thromb Vasc Biol. 2004. PMID: 14739125 Clinical Trial.

5

Pharmaceutical solid-state kinetic stability investigation by using moisture-modified Arrhenius equation and JMP statistical software.

Fu M, Perlman M, Lu Q, Varga C. Fu M, et al. J Pharm Biomed Anal. 2015 Mar 25;107:370-7. doi: 10.1016/j.jpba.2015.01.014. Epub 2015 Jan 13. J Pharm Biomed Anal. 2015. PMID: 25656488

6

Solution-phase, parallel synthesis and pharmacological evaluation of acylguanidine derivatives as potential sodium channel blockers.

Padmanabhan S, Lavin RC, Thakker PM, Guo J, Zhang L, Moore D, Perlman ME, Kirk C, Daly D, Burke-Howie KJ, Wolcott T, Chari S, Berlove D, Fischer JB, Holt WF, Durant GJ, McBurney RN. Padmanabhan S, et al. Among authors: perlman me. Bioorg Med Chem Lett. 2001 Dec 17;11(24):3151-5. doi: 10.1016/s0960-894x(01)00644-8. Bioorg Med Chem Lett. 2001. PMID: 11720863

7

Identification and characterization of a potential ischemia-selective N-methyl-D-aspartate (NMDA) receptor ion-channel blocker, CNS 5788.

Padmanabhan S, Perlman ME, Zhang L, Moore D, Zhou D, Fischer JB, Durant GJ, McBurney RN. Padmanabhan S, et al. Among authors: perlman me. Bioorg Med Chem Lett. 2001 Feb 26;11(4):501-4. doi: 10.1016/s0960-894x(00)00695-8. Bioorg Med Chem Lett. 2001. PMID: 11229757

8

Synthesis and binding characteristics of N-(1-naphthyl)-N'-(3-[(125)I]-iodophenyl)-N'-methylguanidine ([(125)I]-CNS 1261): a potential SPECT agent for imaging NMDA receptor activation.

Owens J, Tebbutt AA, McGregor AL, Kodama K, Magar SS, Perlman ME, Robins DJ, Durant GJ, McCulloch J. Owens J, et al. Among authors: perlman me. Nucl Med Biol. 2000 Aug;27(6):557-64. doi: 10.1016/s0969-8051(00)00102-5. Nucl Med Biol. 2000. PMID: 11056369

9

Synthesis and pharmacological evaluation of N,N'-diarylguanidines as potent sodium channel blockers and anticonvulsant agents.

Reddy NL, Fan W, Magar SS, Perlman ME, Yost E, Zhang L, Berlove D, Fischer JB, Burke-Howie K, Wolcott T, Durant GJ. Reddy NL, et al. Among authors: perlman me. J Med Chem. 1998 Aug 13;41(17):3298-302. doi: 10.1021/jm980134b. J Med Chem. 1998. PMID: 9703475

10

Design, synthesis, and pharmacological evaluation of conformationally constrained analogues of N,N'-diaryl- and N-aryl-N-aralkylguanidines as potent inhibitors of neuronal Na+ channels.

Maillard MC, Perlman ME, Amitay O, Baxter D, Berlove D, Connaughton S, Fischer JB, Guo JQ, Hu LY, McBurney RN, Nagy PI, Subbarao K, Yost EA, Zhang L, Durant GJ. Maillard MC, et al. Among authors: perlman me. J Med Chem. 1998 Jul 30;41(16):3048-61. doi: 10.1021/jm980124a. J Med Chem. 1998. PMID: 9685245

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