Mingozzi F - Search Results

1

Immune responses to AAV in clinical trials.

Mingozzi F, High KA. Mingozzi F, et al. Curr Gene Ther. 2007 Oct;7(5):316-24. doi: 10.2174/156652307782151425. Curr Gene Ther. 2007. PMID: 17979678 Review.

2

Risk and prevention of anti-factor IX formation in AAV-mediated gene transfer in the context of a large deletion of F9.

Fields PA, Arruda VR, Armstrong E, Chu K, Mingozzi F, Hagstrom JN, Herzog RW, High KA. Fields PA, et al. Among authors: mingozzi f. Mol Ther. 2001 Sep;4(3):201-10. doi: 10.1006/mthe.2001.0441. Mol Ther. 2001. PMID: 11545610 Free article.

3

Improved hepatic gene transfer by using an adeno-associated virus serotype 5 vector.

Mingozzi F, Schüttrumpf J, Arruda VR, Liu Y, Liu YL, High KA, Xiao W, Herzog RW. Mingozzi F, et al. J Virol. 2002 Oct;76(20):10497-502. doi: 10.1128/jvi.76.20.10497-10502.2002. J Virol. 2002. PMID: 12239326 Free PMC article.

4

Induction of immune tolerance to coagulation factor IX antigen by in vivo hepatic gene transfer.

Mingozzi F, Liu YL, Dobrzynski E, Kaufhold A, Liu JH, Wang Y, Arruda VR, High KA, Herzog RW. Mingozzi F, et al. J Clin Invest. 2003 May;111(9):1347-56. doi: 10.1172/JCI16887. J Clin Invest. 2003. PMID: 12727926 Free PMC article.

5

Safety and efficacy of factor IX gene transfer to skeletal muscle in murine and canine hemophilia B models by adeno-associated viral vector serotype 1.

Arruda VR, Schuettrumpf J, Herzog RW, Nichols TC, Robinson N, Lotfi Y, Mingozzi F, Xiao W, Couto LB, High KA. Arruda VR, et al. Among authors: mingozzi f. Blood. 2004 Jan 1;103(1):85-92. doi: 10.1182/blood-2003-05-1446. Epub 2003 Sep 11. Blood. 2004. PMID: 12969984 Free PMC article.

6

Induction of antigen-specific CD4+ T-cell anergy and deletion by in vivo viral gene transfer.

Dobrzynski E, Mingozzi F, Liu YL, Bendo E, Cao O, Wang L, Herzog RW. Dobrzynski E, et al. Among authors: mingozzi f. Blood. 2004 Aug 15;104(4):969-77. doi: 10.1182/blood-2004-03-0847. Epub 2004 Apr 22. Blood. 2004. PMID: 15105293 Free article.

7

Therapeutic levels of factor IX expression using a muscle-specific promoter and adeno-associated virus serotype 1 vector.

Liu YL, Mingozzi F, Rodriguéz-Colôn SM, Joseph S, Dobrzynski E, Suzuki T, High KA, Herzog RW. Liu YL, et al. Among authors: mingozzi f. Hum Gene Ther. 2004 Aug;15(8):783-92. doi: 10.1089/1043034041648453. Hum Gene Ther. 2004. PMID: 15319035

8

Major role of local immune responses in antibody formation to factor IX in AAV gene transfer.

Wang L, Cao O, Swalm B, Dobrzynski E, Mingozzi F, Herzog RW. Wang L, et al. Among authors: mingozzi f. Gene Ther. 2005 Oct;12(19):1453-64. doi: 10.1038/sj.gt.3302539. Gene Ther. 2005. PMID: 15889137

9

Identification of mouse AAV capsid-specific CD8+ T cell epitopes.

Sabatino DE, Mingozzi F, Hui DJ, Chen H, Colosi P, Ertl HC, High KA. Sabatino DE, et al. Among authors: mingozzi f. Mol Ther. 2005 Dec;12(6):1023-33. doi: 10.1016/j.ymthe.2005.09.009. Epub 2005 Nov 2. Mol Ther. 2005. PMID: 16263332 Free article.

10

Successful transduction of liver in hemophilia by AAV-Factor IX and limitations imposed by the host immune response.

Manno CS, Pierce GF, Arruda VR, Glader B, Ragni M, Rasko JJ, Ozelo MC, Hoots K, Blatt P, Konkle B, Dake M, Kaye R, Razavi M, Zajko A, Zehnder J, Rustagi PK, Nakai H, Chew A, Leonard D, Wright JF, Lessard RR, Sommer JM, Tigges M, Sabatino D, Luk A, Jiang H, Mingozzi F, Couto L, Ertl HC, High KA, Kay MA. Manno CS, et al. Among authors: mingozzi f. Nat Med. 2006 Mar;12(3):342-7. doi: 10.1038/nm1358. Epub 2006 Feb 12. Nat Med. 2006. PMID: 16474400 Clinical Trial.

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