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2-Arylhydrazinylidene-3-oxo-3-polyfluoroalkylpropanoic acids as selective and effective carboxylesterase inhibitors with powerful antioxidant potential.
Burgart YV, Makhaeva GF, Khudina OG, Krasnykh OP, Kovaleva NV, Elkina NA, Boltneva NP, Rudakova EV, Lushchekina SV, Shchegolkov EV, Triandafilova GA, Malysheva KO, Serebryakova OG, Borisevich SS, Ilyina MG, Zhilina EF, Saloutin VI, Charushin VN, Richardson RJ. Burgart YV, et al. Among authors: richardson rj. Bioorg Med Chem. 2024 Dec 1;115:117938. doi: 10.1016/j.bmc.2024.117938. Epub 2024 Oct 3. Bioorg Med Chem. 2024. PMID: 39504592
Combining Experimental and Computational Methods to Produce Conjugates of Anticholinesterase and Antioxidant Pharmacophores with Linker Chemistries Affecting Biological Activities Related to Treatment of Alzheimer's Disease.
Makhaeva GF, Kovaleva NV, Rudakova EV, Boltneva NP, Lushchekina SV, Astakhova TY, Timokhina EN, Serkov IV, Proshin AN, Soldatova YV, Poletaeva DA, Faingold II, Mumyatova VA, Terentiev AA, Radchenko EV, Palyulin VA, Bachurin SO, Richardson RJ. Makhaeva GF, et al. Among authors: richardson rj. Molecules. 2024 Jan 9;29(2):321. doi: 10.3390/molecules29020321. Molecules. 2024. PMID: 38257233 Free PMC article.
Derivatives of 9-phosphorylated acridine as butyrylcholinesterase inhibitors with antioxidant activity and the ability to inhibit β-amyloid self-aggregation: potential therapeutic agents for Alzheimer's disease.
Makhaeva GF, Kovaleva NV, Rudakova EV, Boltneva NP, Lushchekina SV, Astakhova TY, Timokhina EN, Serebryakova OG, Shchepochkin AV, Averkov MA, Utepova IA, Demina NS, Radchenko EV, Palyulin VA, Fisenko VP, Bachurin SO, Chupakhin ON, Charushin VN, Richardson RJ. Makhaeva GF, et al. Among authors: richardson rj. Front Pharmacol. 2023 Aug 9;14:1219980. doi: 10.3389/fphar.2023.1219980. eCollection 2023. Front Pharmacol. 2023. PMID: 37654616 Free PMC article.
Conjugates of Tacrine and Salicylic Acid Derivatives as New Promising Multitarget Agents for Alzheimer's Disease.
Makhaeva GF, Kovaleva NV, Rudakova EV, Boltneva NP, Grishchenko MV, Lushchekina SV, Astakhova TY, Serebryakova OG, Timokhina EN, Zhilina EF, Shchegolkov EV, Ulitko MV, Radchenko EV, Palyulin VA, Burgart YV, Saloutin VI, Bachurin SO, Richardson RJ. Makhaeva GF, et al. Among authors: richardson rj. Int J Mol Sci. 2023 Jan 24;24(3):2285. doi: 10.3390/ijms24032285. Int J Mol Sci. 2023. PMID: 36768608 Free PMC article.
177 results