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Gut microbiota dysbiosis is associated with altered tryptophan metabolism and dysregulated inflammatory response in COVID-19.
Essex M, Millet Pascual-Leone B, Löber U, Kuhring M, Zhang B, Brüning U, Fritsche-Guenther R, Krzanowski M, Fiocca Vernengo F, Brumhard S, Röwekamp I, Anna Bielecka A, Lesker TR, Wyler E, Landthaler M, Mantei A, Meisel C, Caesar S, Thibeault C, Corman VM, Marko L, Suttorp N, Strowig T, Kurth F, Sander LE, Li Y, Kirwan JA, Forslund SK, Opitz B. Essex M, et al. Among authors: caesar s. NPJ Biofilms Microbiomes. 2024 Aug 1;10(1):66. doi: 10.1038/s41522-024-00538-0. NPJ Biofilms Microbiomes. 2024. PMID: 39085233 Free PMC article.
IL-33 controls IL-22-dependent antibacterial defense by modulating the microbiota.
Röwekamp I, Maschirow L, Rabes A, Fiocca Vernengo F, Hamann L, Heinz GA, Mashreghi MF, Caesar S, Milek M, Fagundes Fonseca AC, Wienhold SM, Nouailles G, Yao L, Mousavi S, Bruder D, Boehme JD, Puzianowska-Kuznicka M, Beule D, Witzenrath M; CAPNETZ Study Group; Löhning M, Klose CSN, Heimesaat MM, Diefenbach A, Opitz B. Röwekamp I, et al. Among authors: caesar s. Proc Natl Acad Sci U S A. 2024 May 28;121(22):e2310864121. doi: 10.1073/pnas.2310864121. Epub 2024 May 23. Proc Natl Acad Sci U S A. 2024. PMID: 38781213
Clinically used broad-spectrum antibiotics compromise inflammatory monocyte-dependent antibacterial defense in the lung.
Dörner PJ, Anandakumar H, Röwekamp I, Fiocca Vernengo F, Millet Pascual-Leone B, Krzanowski M, Sellmaier J, Brüning U, Fritsche-Guenther R, Pfannkuch L, Kurth F, Milek M, Igbokwe V, Löber U, Gutbier B, Holstein M, Heinz GA, Mashreghi MF, Schulte LN, Klatt AB, Caesar S, Wienhold SM, Offermanns S, Mack M, Witzenrath M, Jordan S, Beule D, Kirwan JA, Forslund SK, Wilck N, Bartolomaeus H, Heimesaat MM, Opitz B. Dörner PJ, et al. Among authors: caesar s. Nat Commun. 2024 Mar 30;15(1):2788. doi: 10.1038/s41467-024-47149-z. Nat Commun. 2024. PMID: 38555356 Free PMC article.
Appraisal needs to re-start now so doctors can reflect on coronavirus experiences.
Caesar S, Layer G, Alexander R, Banks V, Barasi S, Bews S, Chaudhury B, Cockman P, Conlon M, Dasan S, Feltbower T, Fox D, Hughes S, Jani B, Jelley D, Lewis-Barned N, Mead S, Qureshi K, Twomey P, van Woerden H, Woodhouse J, Yuille F. Caesar S, et al. BMJ. 2020 Oct 19;371:m3987. doi: 10.1136/bmj.m3987. BMJ. 2020. PMID: 33077426 No abstract available.
78 results