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Page 1
The PP2A inhibitor SET regulates natural killer cell IFN-gamma production.
Trotta R, Ciarlariello D, Dal Col J, Allard J 2nd, Neviani P, Santhanam R, Mao H, Becknell B, Yu J, Ferketich AK, Thomas B, Modi A, Blaser BW, Perrotti D, Caligiuri MA. Trotta R, et al. Among authors: ciarlariello d. J Exp Med. 2007 Oct 1;204(10):2397-405. doi: 10.1084/jem.20070419. Epub 2007 Sep 17. J Exp Med. 2007. PMID: 17875674 Free PMC article.
miR-155 regulates IFN-γ production in natural killer cells.
Trotta R, Chen L, Ciarlariello D, Josyula S, Mao C, Costinean S, Yu L, Butchar JP, Tridandapani S, Croce CM, Caligiuri MA. Trotta R, et al. Among authors: ciarlariello d. Blood. 2012 Apr 12;119(15):3478-85. doi: 10.1182/blood-2011-12-398099. Epub 2012 Feb 29. Blood. 2012. PMID: 22378844 Free PMC article.
Overexpression of miR-155 causes expansion, arrest in terminal differentiation and functional activation of mouse natural killer cells.
Trotta R, Chen L, Costinean S, Josyula S, Mundy-Bosse BL, Ciarlariello D, Mao C, Briercheck EL, McConnell KK, Mishra A, Yu L, Croce CM, Caligiuri MA. Trotta R, et al. Among authors: ciarlariello d. Blood. 2013 Apr 18;121(16):3126-34. doi: 10.1182/blood-2012-12-467597. Epub 2013 Feb 19. Blood. 2013. PMID: 23422749 Free PMC article.
PTEN is a negative regulator of NK cell cytolytic function.
Briercheck EL, Trotta R, Chen L, Hartlage AS, Cole JP, Cole TD, Mao C, Banerjee PP, Hsu HT, Mace EM, Ciarlariello D, Mundy-Bosse BL, Garcia-Cao I, Scoville SD, Yu L, Pilarski R, Carson WE 3rd, Leone G, Pandolfi PP, Yu J, Orange JS, Caligiuri MA. Briercheck EL, et al. Among authors: ciarlariello d. J Immunol. 2015 Feb 15;194(4):1832-40. doi: 10.4049/jimmunol.1401224. Epub 2015 Jan 16. J Immunol. 2015. PMID: 25595786 Free PMC article.
Src homology 2 domain-containing inositol-5-phosphatase and CCAAT enhancer-binding protein beta are targeted by miR-155 in B cells of Emicro-MiR-155 transgenic mice.
Costinean S, Sandhu SK, Pedersen IM, Tili E, Trotta R, Perrotti D, Ciarlariello D, Neviani P, Harb J, Kauffman LR, Shidham A, Croce CM. Costinean S, et al. Among authors: ciarlariello d. Blood. 2009 Aug 13;114(7):1374-82. doi: 10.1182/blood-2009-05-220814. Epub 2009 Jun 11. Blood. 2009. PMID: 19520806 Free PMC article.
Elotuzumab directly enhances NK cell cytotoxicity against myeloma via CS1 ligation: evidence for augmented NK cell function complementing ADCC.
Collins SM, Bakan CE, Swartzel GD, Hofmeister CC, Efebera YA, Kwon H, Starling GC, Ciarlariello D, Bhaskar S, Briercheck EL, Hughes T, Yu J, Rice A, Benson DM Jr. Collins SM, et al. Among authors: ciarlariello d. Cancer Immunol Immunother. 2013 Dec;62(12):1841-9. doi: 10.1007/s00262-013-1493-8. Epub 2013 Oct 26. Cancer Immunol Immunother. 2013. PMID: 24162108 Free PMC article.